Cheng-Kui Qu, MD, PhD
-
Research Program
-
Phone Number
-
Email Address
Biography
Cheng-Kui Qu, MD, PhD is a professor in the Department of Pediatrics at Emory University School of Medicine. Dr. Qu serves as co-leader of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.
Education
Dr. Qu received his Medical Degree from Anhui Medical University in China. He then earned his PhD in Experimental Hematology from the Chinese Academy of Medical Sciences in China. He completed his fellowship in the Department of Biochemistry and Molecular Biology, Walther Oncology Center, Indiana University School of Medicine in Indianapolis, Indiana.
Titles & Roles
-
Professor, Department of PediatricsEmory University School of Medicine
-
Co-Leader, Cell and Molecular Biology Research ProgramWinship Cancer Institute of Emory University
Grants
-
Grant Number Title 2R01HL130995-05A1 Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment 5R01HL130995-06 Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment 5R01HL130995-07 Germline mutations of PTPN11 (SHP2) in the stem cell microenvironment Publications
Dr. Qu has been published in numerous scientific peer-reviewed journals. He serves on the editorial board of Blood Advances.
Title/Journal Authors Publication Date Mitochondrial metabolic flexibility is critical for CD8+ T cell antitumor immunity.
Science advances
C Chen, H Zheng, EM Horwitz, S Ando, K Araki, P Zhao, Z Li, ML Ford, R Ahmed, CK Qu 08/12/2023 AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling.
Stem cell research & therapy
D Li, LC Armand, F Sun, H Hwang, D Wolfson, A Rampoldi, R Liu, P Forghani, X Hu, WM Yu, CK Qu, DP Jones, R Wu, HC Cho, JT Maxwell, C Xu 08/11/2023 eLife
H Zheng, Q Li, S Li, Z Li, M Brotto, D Weiss, D Prosdocimo, C Xu, A Reddy, M Puchowicz, X Zhao, MN Weitzmann, MK Jain, CK Qu 06/09/2023 Scientific reports
Y Yan, C Chen, Z Li, J Zhang, N Park, CK Qu 17/12/2022 Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells.
Cell chemical biology
R Zhang, D Chen, H Fan, R Wu, J Tu, FQ Zhang, M Wang, H Zheng, CK Qu, SE Elf, B Faubert, YY He, MB Bissonnette, X Gao, RJ DeBerardinis, J Chen 21/07/2022 Blood advances
Y Yan, L Dong, C Chen, KD Bunting, Q Li, E Stieglitz, ML Loh, CK Qu 11/01/2022 Methylation of dual-specificity phosphatase 4 controls cell differentiation.
Cell reports
H Su, M Jiang, C Senevirathne, S Aluri, T Zhang, H Guo, J Xavier-Ferrucio, S Jin, NT Tran, SM Liu, CW Sun, Y Zhu, Q Zhao, Y Chen, L Cable, Y Shen, J Liu, CK Qu, X Han, CA Klug, R Bhatia, Y Chen, SD Nimer, YG Zheng, C Iancu-Rubin, J Jin, H Deng, DS Krause, J Xiang, A Verma, M Luo, X Zhao 27/07/2021 Decreased cell stiffness enhances leukemia development and progression.
Leukemia
L Hu, F Ni, X Wang, ME Fay, KM Young, WA Lam, TA Sulchek, CK Qu 01/09/2020 Germline mutations: many roles in leukemogenesis.
Current opinion in hematology
KZ Chen, R Kazi, CC Porter, CK Qu 01/07/2020 Journal of molecular and cellular cardiology
C Gentillon, D Li, M Duan, WM Yu, MK Preininger, R Jha, A Rampoldi, A Saraf, GC Gibson, CK Qu, LA Brown, C Xu 01/07/2019 Ptpn21 Controls Hematopoietic Stem Cell Homeostasis and Biomechanics.
Cell stem cell
F Ni, WM Yu, X Wang, ME Fay, KM Young, Y Qiu, WA Lam, TA Sulchek, T Cheng, DT Scadden, CK Qu 04/04/2019 Nature metabolism
F Ni, WM Yu, Z Li, DK Graham, L Jin, S Kang, MR Rossi, S Li, HE Broxmeyer, CK Qu 01/03/2019 Journal of medicinal chemistry
X Wu, G Xu, X Li, W Xu, Q Li, W Liu, KA Kirby, ML Loh, J Li, SG Sarafianos, CK Qu 14/02/2019 The Journal of pathology
J Gagné-Sansfacon, A Langlois, MJ Langlois, G Coulombe, S Tremblay, V Vaillancourt-Lavigueur, CK Qu, A Menendez, N Rivard 01/01/2019 Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.
Cancer discovery
Y Hayashi, Y Zhang, A Yokota, X Yan, J Liu, K Choi, B Li, G Sashida, Y Peng, Z Xu, R Huang, L Zhang, GM Freudiger, J Wang, Y Dong, Y Zhou, J Wang, L Wu, J Bu, A Chen, X Zhao, X Sun, K Chetal, A Olsson, M Watanabe, LE Romick-Rosendale, H Harada, LY Shih, W Tse, JP Bridges, MA Caligiuri, T Huang, Y Zheng, DP Witte, QF Wang, CK Qu, N Salomonis, HL Grimes, SD Nimer, Z Xiao, G Huang 01/11/2018 Germline mutations in the bone marrow microenvironment and dysregulated hematopoiesis.
Experimental hematology
LH Miller, CK Qu, M Pauly 01/10/2018 Science advances
H Zheng, WM Yu, J Shen, S Kang, D Hambardzumyan, JY Li, Y Shen, AM Kenney, J Chen, CK Qu 01/10/2018 MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation.
Cancer cell
L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, D Wang, G Zhang, J Fan, TJ Boggon, L Zhou, J Kowalski, CK Qu, CE Steuer, GZ Chen, NF Saba, LH Boise, TK Owonikoko, FR Khuri, KR Magliocca, DM Shin, S Lonial, S Kang 13/08/2018 Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice.
Oncotarget
SP Tarnawsky, WM Yu, CK Qu, RJ Chan, MC Yoder 24/04/2018 Science signaling
H Zheng, WM Yu, RR Waclaw, MI Kontaridis, BG Neel, CK Qu 20/03/2018 Molecular cell
L Jin, J Chun, C Pan, A Kumar, G Zhang, Y Ha, D Li, GN Alesi, Y Kang, L Zhou, WM Yu, KR Magliocca, FR Khuri, CK Qu, C Metallo, TK Owonikoko, S Kang 04/01/2018 Leukemia
HA O'Leary, M Capitano, S Cooper, C Mantel, HS Boswell, R Kapur, B Ramdas, R Chan, L Deng, CK Qu, HE Broxmeyer 01/11/2017 Blood
L Dong, H Zheng, CK Qu 21/09/2017 Leukemia
W Liu, WM Yu, J Zhang, RJ Chan, ML Loh, Z Zhang, KD Bunting, CK Qu 01/06/2017 Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Nature
L Dong, WM Yu, H Zheng, ML Loh, ST Bunting, M Pauly, G Huang, M Zhou, HE Broxmeyer, DT Scadden, CK Qu 10/11/2016 Leukemia research
HS Sabnis, HL Bradley, S Tripathi, WM Yu, W Tse, CK Qu, KD Bunting 01/11/2016 Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment.
Cancer cell
L Gu, H Zhang, T Liu, S Zhou, Y Du, J Xiong, S Yi, CK Qu, H Fu, M Zhou 10/10/2016 Oncotarget
J Gagné-Sansfaçon, G Coulombe, MJ Langlois, A Langlois, M Paquet, J Carrier, GS Feng, CK Qu, N Rivard 04/10/2016 A metabolic stress-induced cell cycle checkpoint in stem cells.
Cell cycle (Georgetown, Tex.)
F Ni, CK Qu 01/10/2016 Microenvironmental regulation of hematopoietic stem cells and its implications in leukemogenesis.
Current opinion in hematology
M Seshadri, CK Qu 01/07/2016 Proceedings of the National Academy of Sciences of the United States of America
X Liu, H Zheng, X Li, S Wang, HJ Meyerson, W Yang, BG Neel, CK Qu 26/01/2016 Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism.
Blood
X Liu, H Zheng, WM Yu, TM Cooper, KD Bunting, CK Qu 05/03/2015 Flow cytometric analysis of signaling and apoptosis in hematopoietic stem cells.
Methods in molecular biology (Clifton, N.J.)
L Dong, CK Qu 01/01/2014 The hematopoietic stem cell landscape.
Methods in molecular biology (Clifton, N.J.)
KD Bunting, CK Qu 01/01/2014 Molecular targets for the treatment of juvenile myelomonocytic leukemia.
Advances in hematology
X Liu, H Sabnis, KD Bunting, CK Qu 01/01/2012 Molecular-targeted therapies for hematologic malignancies.
Advances in hematology
KD Bunting, CK Qu, MH Tomasson 01/01/2012 Blood
D Xu, S Wang, WM Yu, G Chan, T Araki, KD Bunting, BG Neel, CK Qu 04/11/2010 Awards
Dr. Qu has earned the following awards and honors:
- Researcher Appreciation Day Recognition, Emory University School of Medicine, 2017, 2018
- Best Scientific Publication of the Year Award, Department of Pediatrics, Emory University, 2016
- Children's Healthcare of Atlanta Research Scholar designation, 2015
- Emory 1% Award, Emory University, 2015