Melinda Pauly, MD

Research Program

Discovery and Developmental Therapeutics
Email Address

melinda.pauly@choa.org

Biography

Melinda G. Pauly, MD, is an associate professor in the Department of Pediatrics at Emory University School of Medicine. Dr. Pauly is a member of the Discovery and Developmental Therapeutics Research Program at Winship.

Education

Dr. Pauly received her medical degree from Medical College of Georgia. She completed her residency at University of Alabama at Birmingham School of Medicine, and her fellowship at Emory University School of Medicine.

Titles & Roles

Associate Professor, Department of Pediatrics

Emory University School of Medicine

View Current Clinical Trials


A Study of SNDX-5613 in Combination With Chemotherapy in Participants With R/R Acute Leukemia Phase I Conditions Relapsed/Refractory Leukemias, Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Mixed Phenotype Acute Leukemia, Acute Myeloid Leukemia, Acute Undifferentiated Leukemia

Title/Journal	Authors	Publication Date
Nivolumab Plus 5-Azacitidine in Pediatric Relapsed/Refractory Acute Myeloid Leukemia (AML): Phase I/II Trial Results from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium. Cancers	A Verma, YY Chi, J Malvar, A Lamble, S Chaudhury, A Agarwal, HT Li, G Liang, R Leong, PA Brown, J Kaplan, ES Schafer, T Slone, M Pauly, BH Chang, E Stieglitz, AS Wayne, N Hijiya, D Bhojwani	24/01/2024
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia. Nature communications	H Mumme, BE Thomas, SS Bhasin, U Krishnan, B Dwivedi, P Perumalla, D Sarkar, GB Ulukaya, HS Sabnis, SI Park, D DeRyckere, SS Raikar, M Pauly, RJ Summers, SM Castellino, DS Wechsler, CC Porter, DK Graham, M Bhasin	05/10/2023
BCMA CAR-T induces complete and durable remission in refractory plasmablastic lymphoma. Journal for immunotherapy of cancer	S Raghunandan, M Pauly, WG Blum, M Qayed, MV Dhodapkar, M Elkhalifa, B Watkins, M Schoettler, E Horwitz, S Parikh, S Chandrakasan, K Leung, E Bryson, L Deeb, JL Kaufman, D Worthington-White, A Alazraki, JM Schecter, D Madduri, CC Jackson, E Zudaire, A Taraseviciute-Morris, A Babich, T Nesheiwat, M Vogel, N Lendvai, L Pacaud, KM Williams	01/05/2023
Mismatched Unrelated Donor Hematopoietic Stem Cell Transplantation Rescues Marrow Failure From Acute Leukemia Therapy in a Patient With Previously Undiagnosed Ligase IV Syndrome. Journal of pediatric hematology/oncology	DM Fridlyand, S Chandrakasan, A Aljudi, WK Aumann, E Westfall, B Kirwan, EW Bryson, FG Keller, SD Arnold, AL Hong, M Pauly, KM Williams	01/01/2023
Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care. JCO precision oncology	RJ Summers, SM Castellino, CC Porter, TJ MacDonald, GD Basu, S Szelinger, MK Bhasin, T Cash, AB Carter, RC Castellino, JR Fangusaro, SG Mitchell, MG Pauly, B Pencheva, DS Wechsler, DK Graham, KC Goldsmith	01/04/2022
Cryptic t(6;11) KMT2A rearrangement in a pediatric acute myeloid leukemia patient detected by next-generation sequencing and dual-fusion FISH analysis. Pediatric blood & cancer	S Raghunandan, J Jain, D Saxe, M Pauly, AA Aljudi, RP Ketterling, AB Carter, SS Raikar	01/03/2022
Immune responses and therapeutic challenges in paediatric patients with new-onset acute myeloid leukaemia and concomitant COVID-19. British journal of haematology	PA Patel, SA Lapp, G Grubbs, VV Edara, CA Rostad, CL Stokes, MG Pauly, EJ Anderson, A Piantadosi, MS Suthar, S Khurana, HS Sabnis	01/08/2021
Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium. Cancer discovery	Y Pikman, SK Tasian, ML Sulis, K Stevenson, TM Blonquist, B Apsel Winger, TM Cooper, M Pauly, KW Maloney, MJ Burke, PA Brown, N Gossai, JL McNeer, NN Shukla, PD Cole, JM Kahn, J Chen, MJ Barth, JA Magee, L Gennarini, AA Adhav, CM Clinton, N Ocasio-Martinez, G Gotti, Y Li, S Lin, A Imamovic, CE Tognon, T Patel, HL Faust, CF Contreras, A Cremer, WA Cortopassi, D Garrido Ruiz, MP Jacobson, NV Dharia, A Su, AL Robichaud, A Saur Conway, K Tarlock, E Stieglitz, AE Place, A Puissant, SP Hunger, AS Kim, NI Lindeman, L Gore, KA Janeway, LB Silverman, JW Tyner, MH Harris, ML Loh, K Stegmaier	01/06/2021
Severe COVID-19 disease in two pediatric oncology patients. Pediatric blood & cancer	CL Stokes, PA Patel, HS Sabnis, SG Mitchell, IB Yildirim, MG Pauly	01/09/2020
Evaluating approaches to enhance survival in children with hypodiploid acute lymphoblastic leukaemia (ALL). British journal of haematology	L Miller, S Kobayashi, M Pauly, G Lew, D Saxe, F Keller, M Qayed, S Castellino	01/05/2019
Germline mutations in the bone marrow microenvironment and dysregulated hematopoiesis. Experimental hematology	LH Miller, CK Qu, M Pauly	01/10/2018
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell	EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, PJ Halfmann, JM Brannan, AS Herbert, X Qiu, K Wagh, S He, EE Giorgi, J Theiler, KBJ Pommert, TB Krause, HL Turner, CD Murin, J Pallesen, E Davidson, R Ahmed, MJ Aman, A Bukreyev, DR Burton, JE Crowe, CW Davis, G Georgiou, F Krammer, CA Kyratsous, JR Lai, C Nykiforuk, MH Pauly, P Rijal, A Takada, AR Townsend, V Volchkov, LM Walker, CI Wang, L Zeitlin, BJ Doranz, AB Ward, B Korber, GP Kobinger, KG Andersen, Y Kawaoka, G Alter, K Chandran, JM Dye	09/08/2018
Phase I trial of the mTOR inhibitor everolimus in combination with multi-agent chemotherapy in relapsed childhood acute lymphoblastic leukemia. Pediatric blood & cancer	AE Place, Y Pikman, KE Stevenson, MH Harris, M Pauly, ML Sulis, N Hijiya, L Gore, TM Cooper, ML Loh, G Roti, DS Neuberg, SK Hunt, S Orloff-Parry, K Stegmaier, SE Sallan, LB Silverman	01/07/2018
Hyperleukocytosis in infant acute leukemia: a role for manual exchange transfusion for leukoreduction. Transfusion	DV Runco, CD Josephson, SS Raikar, KC Goldsmith, G Lew, M Pauly, RM Fasano	01/05/2018
Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R. British journal of haematology	L Giulino-Roth, T O'Donohue, Z Chen, NL Bartlett, A LaCasce, W Martin-Doyle, MJ Barth, K Davies, KA Blum, B Christian, C Casulo, SM Smith, J Godfrey, A Termuhlen, MJ Oberley, S Alexander, S Weitzman, B Appel, B Mizukawa, J Svoboda, Z Afify, M Pauly, H Dave, R Gardner, DM Stephens, WA Zeitler, C Forlenza, J Levine, ME Williams, JL Sima, CM Bollard, JP Leonard	01/12/2017
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment. Nature	L Dong, WM Yu, H Zheng, ML Loh, ST Bunting, M Pauly, G Huang, M Zhou, HE Broxmeyer, DT Scadden, CK Qu	10/11/2016