Carlos Moreno, PhD
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Research Program
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Phone Number
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Email Address
Carlos S. Moreno, PhD, is an associate professor in the Departments of Pathology and Laboratory Medicine, and Biomedical Informatics at the Emory University School of Medicine. Dr. Moreno serves as assistant director for education and training and is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute of Emory University.
Dr. Moreno specializes in cancer bioinformatics and systems biology, analysis of genome-wide expression profiles, transcriptional networks, ChIP-chip studies, biological pathway analysis, and computational analysis of transcription factor binding sites. Dr. Moreno is project leader for informatics for the Emory Molecular Interaction Center for Functional genomics (MicFG) as part of the Cancer Target Discovery and Development (CTD²) Network to analyze TCGA data for protein-protein interaction networks.
Dr. Moreno earned his BS and MS from Massachusetts Institute of Technology in Cambridge, Massachusetts. He received his PhD from Emory University in Atlanta, Georgia.
Dr. Moreno's main research interests are in translational cancer bioinformatics and systems biology, to identify diagnostic markers for more effective and personalized therapies, to identify new potential therapeutic targets, and to better understand the biology of tumor progression. His research has focused on the dissection of the perturbed transcriptional networks in prostate, brain, breast, and ovarian cancers using DNA microarrays and next generation sequencing. His lab has identified several genes that are strongly correlated with prostate cancer progression, including two developmental transcription factors, HOXC6 and SOX4. His lab is also developing mRNA and microRNA biomarkers of recurrence in prostate cancer. His lab analyzes genome-wide expression profiles, transcriptional networks, ChIP-chip and ChIP-seq studies, biological pathways and evolutionarily conserved transcription factor binding sites to dissect cancer-related transcriptional networks and identify new drug targets and biomarkers. They are heavily involved in analysis of data from The Cancer Genome Atlas project to identify potential drug targets as part of the Cancer Target Discovery and Development (CTD2) Network at NCI.
Title/Journal | Authors | Publication Date |
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Molecular and cellular endocrinology |
AC Camargo, FB Constantino, SA Santos, KT Colombelli, LM Portela, MN Fioretto, LA Barata, GT Valente, CS Moreno, LA Justulin | 15/01/2024 |
Cancers |
CS Moreno, CL Winham, M Alemozaffar, ER Klein, IO Lawal, OA Abiodun-Ojo, D Patil, BG Barwick, Y Huang, DM Schuster, MG Sanda, AO Osunkoya | 30/11/2023 |
Scientific reports |
LMF Portela, FB Constantino, ACL Camargo, SAA Santos, KT Colombelli, MN Fioretto, LA Barata, EJR Silva, WR Scarano, SL Felisbino, CS Moreno, LA Justulin | 31/10/2023 |
New insights into KLFs and SOXs in cancer pathogenesis, stemness, and therapy. Seminars in cancer biology |
L Zeng, Y Zhu, CS Moreno, Y Wan | 01/05/2023 |
High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells. Nature communications |
M Boya, T Ozkaya-Ahmadov, BE Swain, CH Chu, N Asmare, O Civelekoglu, R Liu, D Lee, S Tobia, S Biliya, LD McDonald, B Nazha, O Kucuk, MG Sanda, BB Benigno, CS Moreno, MA Bilen, JF McDonald, AF Sarioglu | 13/06/2022 |
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer. Cell |
X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, A Wahafu, SP Doyle, D Cicka, X Yang, D Fan, MA Reyna, LAD Cooper, CS Moreno, W Zhou, TK Owonikoko, S Lonial, FR Khuri, Y Du, SS Ramalingam, GB Mills, H Fu | 26/05/2022 |
The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology |
V Ouellet, A Erickson, K Wiley, C Morrissey, V Berge, CS Moreno, KA Tasken, D Trudel, LD True, MS Lewis, A Svindland, O Ertunc, ID Vidal, AO Osunkoya, T Jones, GS Bova, T Lamminen, AH Achtman, M Buzza, MM Kouspou, SA Bigler, X Zhou, SJ Freedland, AM Mes-Masson, IP Garraway, BJ Trock, P Taimen, F Saad, T Mirtti, BS Knudsen, AM De Marzo | 01/04/2022 |
Molecular and cellular endocrinology |
AC Camargo, B Remoli, LM Portela, MN Fioretto, LG Chuffa, CS Moreno, LA Justulin | 15/09/2021 |
Cell reports methods |
K Su, Q Yu, R Shen, SY Sun, CS Moreno, X Li, ZS Qin | 23/08/2021 |
BMC genomics |
S Guo, S Huang, X Jiang, H Hu, D Han, CS Moreno, GL Fairbrother, DA Hughes, M Stoneking, P Khaitovich | 20/04/2021 |
Life sciences in space research |
Z Li, KK Jella, L Jaafar, CS Moreno, WS Dynan | 01/02/2021 |
SOX4: The unappreciated oncogene. Seminars in cancer biology |
CS Moreno | 01/12/2020 |
Cytotechnology |
NN Phan, CS Moreno, YH Lai | 01/08/2020 |
Cytotechnology |
NN Phan, CS Moreno, YH Lai | 01/08/2020 |
The Journal of biological chemistry |
B Cinar, MM Al-Mathkour, SA Khan, CS Moreno | 19/06/2020 |
Oncogene |
AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, NT Pfister, R Haji-Seyed-Javadi, H Zhang, J Xu, N Deng, DM Duong, TJ Pecen, Z Frazier, ZD Nagel, JB Lazaro, KW Mouw, NT Seyfried, CS Moreno, TK Owonikoko, X Deng, DS Yu | 01/06/2020 |
Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma. Scientific reports |
ZS Buchwald, S Tian, M Rossi, GH Smith, J Switchenko, JE Hauenstein, CS Moreno, RH Press, RS Prabhu, J Zhong, DF Saxe, SG Neill, JJ Olson, IR Crocker, WJ Curran, HG Shu | 30/04/2020 |
Translational oncology |
Z Li, C Sun, S Tao, AO Osunkoya, RS Arnold, JA Petros, X Zu, CS Moreno | 01/04/2020 |
Scientific reports |
A Ogden, S Bhattarai, B Sahoo, NP Mongan, M Alsaleem, AR Green, M Aleskandarany, IO Ellis, S Pattni, XB Li, CS Moreno, U Krishnamurti, EA Janssen, K Jonsdottir, E Rakha, P Rida, R Aneja | 20/02/2020 |
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression. Molecular cancer research : MCR |
S Chandrasekaran, M Sasaki, CD Scharer, HT Kissick, DG Patterson, KR Magliocca, JT Seykora, B Sapkota, DA Gutman, LA Cooper, GB Lesinski, EK Waller, SN Thomas, SV Kotenko, JM Boss, CS Moreno, RA Swerlick, BP Pollack | 01/12/2019 |
SOX4 regulates invasion of bladder cancer cells via repression of WNT5a. International journal of oncology |
JD Moran, HH Kim, Z Li, CS Moreno | 01/08/2019 |
Clinical breast cancer |
E Paplomata, A Zelnak, CA Santa-Maria, Y Liu, K Gogineni, X Li, CS Moreno, Z Chen, V Kaklamani, RM O'Regan | 01/06/2019 |
Cancers |
NV Sharma, KL Pellegrini, V Ouellet, FO Giuste, S Ramalingam, K Watanabe, E Adam-Granger, L Fossouo, S You, MR Freeman, P Vertino, K Conneely, AO Osunkoya, D Trudel, AM Mes-Masson, JA Petros, F Saad, CS Moreno | 11/10/2018 |
Selective modification of fluciclovine (18F) transport in prostate carcinoma xenografts. Amino acids |
FI Tade, WG Wiles, G Lu, B Bilir, O Akin-Akintayo, JS Lee, D Patil, W Yu, C Ormenisan Gherasim, B Fei, CS Moreno, AO Osunkoya, EJ Teoh, S Oka, H Okudaira, MM Goodman, DM Schuster | 01/09/2018 |
Bioinformatics (Oxford, England) |
AA Ivanov, B Revennaugh, L Rusnak, V Gonzalez-Pecchi, X Mo, MA Johns, Y Du, LAD Cooper, CS Moreno, FR Khuri, H Fu | 01/04/2018 |
Oncotarget |
M Lee, Y Rivera-Rivera, CS Moreno, HI Saavedra | 29/09/2017 |
International journal of oncology |
B Bilir, NV Sharma, J Lee, B Hammarstrom, A Svindland, O Kucuk, CS Moreno | 01/07/2017 |
BJU international |
KL Pellegrini, MG Sanda, D Patil, Q Long, M Santiago-Jiménez, M Takhar, N Erho, K Yousefi, E Davicioni, EA Klein, RB Jenkins, RJ Karnes, CS Moreno | 01/06/2017 |
The Prostate |
KL Pellegrini, D Patil, KJS Douglas, G Lee, K Wehrmeyer, M Torlak, J Clark, CS Cooper, CS Moreno, MG Sanda | 01/06/2017 |
Urologic oncology |
S Vijayakumar, JC Henegan, X Zhang, W Wang, WA Day, V Vijayakumar, CS Moreno, CR Gomez | 01/06/2017 |
Nature communications |
Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, E McMillan, L Rusnak, C Pham, X Chen, X Mo, B Revennaugh, W Zhou, A Marcus, S Harati, X Chen, MA Johns, MA White, CS Moreno, LAD Cooper, Y Du, FR Khuri, H Fu | 18/04/2017 |
Molecular pharmacology |
X Mo, Q Qi, AA Ivanov, Q Niu, Y Luo, J Havel, R Goetze, S Bell, CS Moreno, LA Cooper, MA Johns, FR Khuri, Y Du, H Fu | 01/04/2017 |
Nature communications |
Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, E McMillan, L Rusnak, C Pham, X Chen, X Mo, B Revennaugh, W Zhou, A Marcus, S Harati, X Chen, MA Johns, MA White, C Moreno, LA Cooper, Y Du, FR Khuri, H Fu | 16/02/2017 |
PloS one |
S Harati, LA Cooper, JD Moran, FO Giuste, Y Du, AA Ivanov, MA Johns, FR Khuri, H Fu, CS Moreno | 01/01/2017 |
Proceedings of the National Academy of Sciences of the United States of America |
MR Kudelka, BH Hinrichs, T Darby, CS Moreno, H Nishio, CE Cutler, J Wang, H Wu, J Zeng, Y Wang, T Ju, SR Stowell, A Nusrat, RM Jones, AS Neish, RD Cummings | 20/12/2016 |
Journal of thoracic disease |
CS Moreno | 01/10/2016 |
Gene integrated set profile analysis: a context-based approach for inferring biological endpoints. Nucleic acids research |
J Kowalski, B Dwivedi, S Newman, JM Switchenko, R Pauly, DA Gutman, J Arora, K Gandhi, K Ainslie, G Doho, Z Qin, CS Moreno, MR Rossi, PM Vertino, S Lonial, L Bernal-Mizrachi, LH Boise | 20/04/2016 |
SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation. Cancer research |
B Bilir, AO Osunkoya, WG Wiles, S Sannigrahi, V Lefebvre, D Metzger, DD Spyropoulos, WD Martin, CS Moreno | 01/03/2016 |
Journal of the American Statistical Association |
Y Zhao, M Chung, BA Johnson, CS Moreno, Q Long | 01/01/2016 |
Tissue barriers |
LN Lili, AE Farkas, C Gerner-Smidt, CE Overgaard, CS Moreno, CA Parkos, CT Capaldo, A Nusrat | 01/01/2016 |
RNA biomarkers to facilitate the identification of aggressive prostate cancer. Molecular aspects of medicine |
KL Pellegrini, MG Sanda, CS Moreno | 01/11/2015 |
Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model. Archives of biochemistry and biophysics |
K Sahin, B Cross, N Sahin, K Ciccone, S Suleiman, AO Osunkoya, V Master, W Harris, B Carthon, R Mohammad, B Bilir, K Wertz, CS Moreno, CL Walker, O Kucuk | 15/04/2015 |
Evaluating intra- and inter-individual variation in the human placental transcriptome. Genome biology |
DA Hughes, M Kircher, Z He, S Guo, GL Fairbrother, CS Moreno, P Khaitovich, M Stoneking | 19/03/2015 |
Cancer research |
G Chen, J Kong, C Tucker-Burden, M Anand, Y Rong, F Rahman, CS Moreno, EG Van Meir, CG Hadjipanayis, DJ Brat | 15/08/2014 |
E2F activators signal and maintain centrosome amplification in breast cancer cells. Molecular and cellular biology |
MY Lee, CS Moreno, HI Saavedra | 01/07/2014 |
Cancer research |
Q Long, J Xu, AO Osunkoya, S Sannigrahi, BA Johnson, W Zhou, T Gillespie, JY Park, RK Nam, L Sugar, A Stanimirovic, AK Seth, JA Petros, CS Moreno | 15/06/2014 |
Evaluation and program planning |
KJ Wells, DS Lima, CD Meade, T Muñoz-Antonia, I Scarinci, A McGuire, CK Gwede, WJ Pledger, E Partridge, J Lipscomb, R Matthews, J Matta, I Flores, R Weiner, T Turner, L Miele, TE Wiese, M Fouad, CS Moreno, M Lacey, DW Christie, EG Price-Haywood, GP Quinn, D Coppola, SO Sodeke, BL Green, MY Lichtveld | 01/06/2014 |
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc |
KE Fisher, Q Yin-Goen, D Alexis, JS Sirintrapun, W Harrison, R Benjamin Isett, MR Rossi, CS Moreno, AN Young, AO Osunkoya | 01/02/2014 |
Cancer informatics |
R Yang, L Chen, S Newman, K Gandhi, G Doho, CS Moreno, PM Vertino, L Bernal-Mizarchi, S Lonial, LH Boise, M Rossi, J Kowalski, ZS Qin | 01/01/2014 |
Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality. In vivo (Athens, Greece) |
WG Wiles, Z Mou, Y Du, AB Long, CD Scharer, B Bilir, DD Spyropoulos, NA Jenkins, NG Copeland, WD Martin, CS Moreno | 01/01/2014 |
Proceedings. IEEE International Conference on Bioinformatics and Biomedicine |
J Kong, F Wang, G Teodoro, L Cooper, CS Moreno, T Kurc, T Pan, J Saltz, D Brat | 01/12/2013 |
Wnt signaling in triple negative breast cancer is associated with metastasis. BMC cancer |
N Dey, BG Barwick, CS Moreno, M Ordanic-Kodani, Z Chen, G Oprea-Ilies, W Tang, C Catzavelos, KF Kerstann, GW Sledge, M Abramovitz, M Bouzyk, P De, BR Leyland-Jones | 10/11/2013 |
Journal of translational medicine |
B Bilir, O Kucuk, CS Moreno | 04/11/2013 |
Clinical cancer research : an official journal of the American Association for Cancer Research |
WC Rutledge, J Kong, J Gao, DA Gutman, LA Cooper, C Appin, Y Park, L Scarpace, T Mikkelsen, ML Cohen, KD Aldape, RE McLendon, NL Lehman, CR Miller, MJ Schniederjan, CW Brennan, JH Saltz, CS Moreno, DJ Brat | 15/09/2013 |
Radiology |
DA Gutman, LA Cooper, SN Hwang, CA Holder, J Gao, TD Aurora, WD Dunn, L Scarpace, T Mikkelsen, R Jain, M Wintermark, M Jilwan, P Raghavan, E Huang, RJ Clifford, P Mongkolwat, V Kleper, J Freymann, J Kirby, PO Zinn, CS Moreno, C Jaffe, R Colen, DL Rubin, J Saltz, A Flanders, DJ Brat | 01/05/2013 |
Brain research |
JV Pulliam, Z Xu, GD Ford, C Liu, Y Li, KC Stovall, VS Cannon, T Tewolde, CS Moreno, BD Ford | 07/02/2013 |
American journal of nuclear medicine and molecular imaging |
DM Schuster, PA Taleghani, PT Nieh, VA Master, R Amzat, B Savir-Baruch, RK Halkar, T Fox, AO Osunkoya, CS Moreno, JA Nye, W Yu, B Fei, Z Wang, Z Chen, MM Goodman | 01/01/2013 |
PloS one |
J Kong, LA Cooper, F Wang, J Gao, G Teodoro, L Scarpace, T Mikkelsen, MJ Schniederjan, CS Moreno, JH Saltz, DJ Brat | 01/01/2013 |
The American journal of pathology |
LA Cooper, DA Gutman, C Chisolm, C Appin, J Kong, Y Rong, T Kurc, EG Van Meir, JH Saltz, CS Moreno, DJ Brat | 01/05/2012 |
BMC cancer |
CJ Phillip, CK Giardina, B Bilir, DJ Cutler, YH Lai, O Kucuk, CS Moreno | 11/04/2012 |
Integrated morphologic analysis for the identification and characterization of disease subtypes. Journal of the American Medical Informatics Association : JAMIA |
LA Cooper, J Kong, DA Gutman, F Wang, J Gao, C Appin, S Cholleti, T Pan, A Sharma, L Scarpace, T Mikkelsen, T Kurc, CS Moreno, DJ Brat, JH Saltz | 01/01/2012 |
IEEE transactions on bio-medical engineering |
J Kong, LA Cooper, F Wang, DA Gutman, J Gao, C Chisolm, A Sharma, T Pan, EG Van Meir, TM Kurc, CS Moreno, JH Saltz, DJ Brat | 01/12/2011 |
SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC cell biology |
YH Lai, J Cheng, D Cheng, ME Feasel, KD Beste, J Peng, A Nusrat, CS Moreno | 19/11/2011 |
Apoptosis : an international journal on programmed cell death |
L Qi, AC Bellail, MR Rossi, Z Zhang, H Pang, S Hunter, C Cohen, CS Moreno, JJ Olson, S Li, C Hao | 01/11/2011 |
BMC biochemistry |
J Gordon, J Hwang, KJ Carrier, CA Jones, QL Kern, CS Moreno, RH Karas, DC Pallas | 10/10/2011 |
The annals of applied statistics |
Q Long, M Chung, CS Moreno, BA Johnson | 01/09/2011 |
The American journal of pathology |
Q Long, BA Johnson, AO Osunkoya, YH Lai, W Zhou, M Abramovitz, M Xia, MB Bouzyk, RK Nam, L Sugar, A Stanimirovic, DJ Williams, BR Leyland-Jones, AK Seth, JA Petros, CS Moreno | 01/07/2011 |
Proceedings. IEEE International Symposium on Biomedical Imaging |
J Kong, L Cooper, F Wang, C Chisolm, C Moreno, T Kurc, P Widener, D Brat, J Saltz | 30/03/2011 |
MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA. Proceedings. IEEE International Symposium on Biomedical Imaging |
LA Cooper, J Kong, F Wang, T Kurc, CS Moreno, DJ Brat, JH Saltz | 30/03/2011 |
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference |
J Kong, L Cooper, C Moreno, F Wang, T Kurc, J Saltz, D Brat | 01/01/2011 |
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society |
BM Shehata, M Bouzyk, SC Shulman, W Tang, CK Steelman, GK Davis, CS Moreno | 01/01/2011 |
An integrative approach for in silico glioma research. IEEE transactions on bio-medical engineering |
LA Cooper, J Kong, DA Gutman, F Wang, SR Cholleti, TC Pan, PM Widener, A Sharma, T Mikkelsen, AE Flanders, DL Rubin, EG Van Meir, TM Kurc, CS Moreno, DJ Brat, JH Saltz | 01/10/2010 |
PloS one |
LA Cooper, DA Gutman, Q Long, BA Johnson, SR Cholleti, T Kurc, JH Saltz, DJ Brat, CS Moreno | 03/09/2010 |
British journal of cancer |
BG Barwick, M Abramovitz, M Kodani, CS Moreno, R Nam, W Tang, M Bouzyk, A Seth, B Leyland-Jones | 02/02/2010 |
The American journal of pathology |
CS Moreno | 01/02/2010 |
Identification of a novel small molecule HIF-1alpha translation inhibitor. Clinical cancer research : an official journal of the American Association for Cancer Research |
T Narita, S Yin, CF Gelin, CS Moreno, M Yepes, KC Nicolaou, EG Van Meir | 01/10/2009 |
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells. Cancer research |
CD Scharer, CD McCabe, M Ali-Seyed, MF Berger, ML Bulyk, CS Moreno | 15/01/2009 |
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. Journal of translational medicine |
CD Scharer, N Laycock, AO Osunkoya, S Logani, JF McDonald, BB Benigno, CS Moreno | 11/12/2008 |
Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Molecular cancer research : MCR |
L Guo, D Zhong, S Lau, X Liu, XY Dong, X Sun, VW Yang, PM Vertino, CS Moreno, V Varma, JT Dong, W Zhou | 01/09/2008 |
Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer. Cancer research |
CD McCabe, DD Spyropoulos, D Martin, CS Moreno | 15/03/2008 |
Optimization of RNA extraction from FFPE tissues for expression profiling in the DASL assay. BioTechniques |
M Abramovitz, M Ordanic-Kodani, Y Wang, Z Li, C Catzavelos, M Bouzyk, GW Sledge, CS Moreno, B Leyland-Jones | 01/03/2008 |
Genomic promoter analysis predicts functional transcription factor binding. Advances in bioinformatics |
JS Rao, S Karanam, CD McCabe, CS Moreno | 01/01/2008 |
Pituitary |
CO Evans, CS Moreno, X Zhan, MT McCabe, PM Vertino, DM Desiderio, NM Oyesiku | 01/01/2008 |
PloS one |
CS Moreno, L Matyunina, EB Dickerson, N Schubert, NJ Bowen, S Logani, BB Benigno, JF McDonald | 16/05/2007 |
Expression microarray analysis of brain tumors: what have we learned so far. Frontiers in bioscience : a journal and virtual library |
SB Hunter, CS Moreno | 01/08/2002 |