Tobey MacDonald, MD
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Research Program
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Phone Number
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Email Address
Biography
Tobey J. MacDonald, MD, is board certified in pediatrics and pediatric hematology and oncology by the American Board of Pediatrics.
Dr. MacDonald is member of the Cell and Molecular Biology Research Program at Winship Cancer Institute.
Education
Dr. MacDonald received his medical degree from Cornell University in New York City, NY. He then completed a residency in pediatrics and fellowships in pediatric hematology and oncology, and pediatric neuro-oncology at the Children's Hospital Los Angeles in Los Angeles, CA.
Titles & Roles
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Professor, Department of PediatricsEmory University School of Medicine
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Director, Pediatric Neuro-Oncology ProgramAflac Cancer and Blood Disorders Center
Professional Memberships
Dr. MacDonald is a member of the Society for Neuro-Oncology, the American Association for Cancer Research and the American Society for Pediatric Hematology/Oncology.
Research
Dr. MacDonald's research areas of interest include basic and translational research of childhood brain tumors with a primary research focus on the metastasis and role of platelet-derived growth factor receptor (PDGFR) signaling basic and translational research of childhood brain tumors with a primary research focus on the metastasis and role of platelet-derived growth factor receptor (PDGFR) signaling.
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Grants
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Title/Journal Authors Publication Date Neuro-oncology
Y Odia, C Koschmann, NA Vitanza, P de Blank, D Aguilera, J Allen, D Daghistani, M Hall, Z Khatib, C Kline, T MacDonald, S Mueller, SL Faison, JE Allen, OJ Naderer, SC Ramage, RS Tarapore, SL McGovern, S Khatua, W Zaky, SL Gardner 03/05/2024 ONC201 (Dordaviprone) in Recurrent H3 K27M-Mutant Diffuse Midline Glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
I Arrillaga-Romany, SL Gardner, Y Odia, D Aguilera, JE Allen, T Batchelor, N Butowski, C Chen, T Cloughesy, A Cluster, J de Groot, KS Dixit, JJ Graber, AM Haggiagi, RA Harrison, A Kheradpour, LB Kilburn, SC Kurz, G Lu, TJ MacDonald, M Mehta, AS Melemed, PL Nghiemphu, SC Ramage, N Shonka, A Sumrall, RS Tarapore, L Taylor, Y Umemura, PY Wen 01/05/2024 DNA Methylation Profiles Are Stable in H3 K27M-Mutant Diffuse Midline Glioma Neurosphere Cell Lines.
Children (Basel, Switzerland)
MJ Schniederjan, C Potnis, V Vasudevaraja, CD Moser, B Watson, M Snuderl, T MacDonald, BB Rogers 20/04/2024 Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial.
Neuro-oncology
TS Johnson, TJ MacDonald, R Pacholczyk, D Aguilera, A Al-Basheer, M Bajaj, P Bandopadhayay, Z Berrong, E Bouffet, RC Castellino, K Dorris, BR Eaton, N Esiashvili, JR Fangusaro, N Foreman, D Fridlyand, C Giller, IM Heger, C Huang, N Kadom, EP Kennedy, N Manoharan, W Martin, C McDonough, RS Parker, V Ramaswamy, E Ring, A Rojiani, RF Sadek, S Satpathy, M Schniederjan, A Smith, C Smith, BE Thomas, R Vaizer, KK Yeo, MK Bhasin, DH Munn 02/02/2024 Visual outcomes after bevacizumab-based therapy for optic pathway glioma.
Pediatric blood & cancer
BI Siegel, D Nelson, JH Peragallo, TJ MacDonald, DS Wolf 01/12/2023 The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival.
Molecular oncology
SW Shahab, CM Roggeveen, J Sun, H Kunhiraman, LF McSwain, K Juraschka, SA Kumar, O Saulnier, MD Taylor, M Schniederjan, RW Schnepp, TJ MacDonald, AM Kenney 01/09/2023 Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
Scientific reports
LF McSwain, CE Pillsbury, R Haji-Seyed-Javadi, SK Rath, V Chen, T Huang, SW Shahab, H Kunhiraman, J Ross, GA Price, A Dey, D Hambardzumyan, T MacDonald, DS Yu, CC Porter, AM Kenney 15/06/2023 YB1 modulates the DNA damage response in medulloblastoma.
Scientific reports
LF McSwain, CE Pillsbury, R Haji-Seyed-Javadi, SK Rath, V Chen, T Huang, SW Shahab, H Kunhiraman, J Ross, GA Price, A Dey, D Hambardzumyan, T MacDonald, DS Yu, CC Porter, AM Kenney 19/05/2023 Acta neuropathologica communications
H Kunhiraman, L McSwain, SW Shahab, TR Gershon, TJ MacDonald, AM Kenney 08/04/2023 Neuro-oncology
KK Yeo, S Alexandrescu, JA Cotter, J Vogelzang, V Bhave, MM Li, J Ji, JK Benhamida, MK Rosenblum, TA Bale, N Bouvier, K Kaneva, T Rosenberg, MJ Lim-Fat, H Ghosh, M Martinez, D Aguilera, A Smith, S Goldman, EL Diamond, I Gavrilovic, TJ MacDonald, MD Wood, KJ Nazemi, A Truong, A Cluster, KL Ligon, K Cole, WL Bi, AS Margol, MA Karajannis, KD Wright 05/01/2023 Case report: ATIC-ALK fusion in infant-type hemispheric glioma and response to lorlatinib.
Frontiers in oncology
SW Shahab, M Schniederjan, JV Vega, S Little, A Reisner, T MacDonald, D Aguilera 01/01/2023 Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma.
Neuro-oncology
T Rosenberg, KK Yeo, A Mauguen, S Alexandrescu, SP Prabhu, JW Tsai, S Malinowski, M Joshirao, K Parikh, S Farouk Sait, MK Rosenblum, JK Benhamida, G Michaiel, HN Tran, S Dahiya, K Kachurak, GK Friedman, JI Krystal, MA Huang, AS Margol, KD Wright, D Aguilera, TJ MacDonald, SN Chi, MA Karajannis 02/11/2022 Journal of neuropathology and experimental neurology
SB Shively, NA Edwards, TJ MacDonald, KR Johnson, NM Diaz-Rodriguez, MJ Merrill, AO Vortmeyer 18/10/2022 CNS oncology
J Groot, M Ott, J Wei, C Kassab, D Fang, H Najem, B O'Brien, SP Weathers, CK Matsouka, NK Majd, RA Harrison, GN Fuller, JT Huse, JP Long, R Sawaya, G Rao, TJ MacDonald, W Priebe, M DeCuypere, AB Heimberger 01/06/2022 Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
RJ Kautiainen, C Keeler, B Dwivedi, TJ MacDonald, TZ King 01/04/2022 JCO precision oncology
RJ Summers, SM Castellino, CC Porter, TJ MacDonald, GD Basu, S Szelinger, MK Bhasin, T Cash, AB Carter, RC Castellino, JR Fangusaro, SG Mitchell, MG Pauly, B Pencheva, DS Wechsler, DK Graham, KC Goldsmith 01/04/2022 Molecular oncology
L Yuan, H Zhang, J Liu, A Malhotra, A Dey, B Yu, KK Jella, LF McSwain, MJ Schniederjan, TJ MacDonald 01/02/2022 Medulloblastoma and the DNA Damage Response.
Frontiers in oncology
LF McSwain, KK Parwani, SW Shahab, D Hambardzumyan, TJ MacDonald, JM Spangle, AM Kenney 01/01/2022 Neuro-oncology advances
SL Gardner, RS Tarapore, J Allen, SL McGovern, W Zaky, Y Odia, D Daghistani, Z Diaz, MD Hall, Z Khatib, C Koschmann, E Cantor, R Kurokawa, TJ MacDonald, D Aguilera, NA Vitanza, S Mueller, C Kline, G Lu, JE Allen, S Khatua 01/01/2022 Tumour immune landscape of paediatric high-grade gliomas.
Brain : a journal of neurology
JL Ross, J Velazquez Vega, A Plant, TJ MacDonald, OJ Becher, D Hambardzumyan 22/10/2021 Cancer
BR Eaton, GW Fong, LM Ingerski, MB Pulsifer, S Goyal, C Zhang, EA Weyman, N Esiashvili, JL Klosky, TJ MacDonald, DH Ebb, SM MacDonald, NJ Tarbell, TI Yock 15/10/2021 Science advances
Y Guo, H Lee, Z Fang, A Velalopoulou, J Kim, MB Thomas, J Liu, RG Abramowitz, Y Kim, AF Coskun, DP Krummel, S Sengupta, TJ MacDonald, C Arvanitis 01/04/2021 Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo.
Cancers
TJ MacDonald, J Liu, B Yu, A Malhotra, J Munson, JC Park, K Wang, B Fei, R Bellamkonda, J Arbiser 11/03/2021 Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Brain : a journal of neurology
JL Ross, Z Chen, CJ Herting, Y Grabovska, F Szulzewsky, M Puigdelloses, L Monterroza, J Switchenko, NR Wadhwani, PJ Cimino, A Mackay, C Jones, RD Read, TJ MacDonald, M Schniederjan, OJ Becher, D Hambardzumyan 12/02/2021 Integrated analysis of pediatric low-grade glioma: clinical implications and the path forward.
Neuro-oncology
RJ Packer, TJ MacDonald 14/10/2020 Lipidome signatures of metastasis in a transgenic mouse model of sonic hedgehog medulloblastoma.
Analytical and bioanalytical chemistry
D Huang, J Liu, RC Eldridge, DA Gaul, MRL Paine, K Uppal, TJ MacDonald, FM Fernández 01/10/2020 Proceedings of the National Academy of Sciences of the United States of America
J Kim, A Dey, A Malhotra, J Liu, SI Ahn, YJ Sei, AM Kenney, TJ MacDonald, Y Kim 29/09/2020 Acta neuropathologica
AM Saratsis, M Kambhampati, K Snyder, S Yadavilli, JM Devaney, B Harmon, J Hall, EH Raabe, P An, M Weingart, BR Rood, SN Magge, TJ MacDonald, RJ Packer, J Nazarian 01/08/2020 Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
RJ Kautiainen, B Dwivedi, TJ MacDonald, TZ King 01/08/2020 Subtype and grade-dependent spatial heterogeneity of T-cell infiltration in pediatric glioma.
Journal for immunotherapy of cancer
MH Robinson, J Vasquez, A Kaushal, TJ MacDonald, JE Velázquez Vega, M Schniederjan, K Dhodapkar 01/08/2020 Neuro-oncology
RJ Packer, A Iavarone, DTW Jones, JO Blakeley, E Bouffet, MJ Fisher, E Hwang, C Hawkins, L Kilburn, T MacDonald, SM Pfister, B Rood, FJ Rodriguez, U Tabori, V Ramaswamy, Y Zhu, J Fangusaro, SA Johnston, DH Gutmann 09/06/2020 The Lancet. Oncology
C Erker, B Tamrazi, TY Poussaint, S Mueller, D Mata-Mbemba, E Franceschi, AA Brandes, A Rao, KB Haworth, PY Wen, S Goldman, G Vezina, TJ MacDonald, IJ Dunkel, PS Morgan, T Jaspan, MD Prados, KE Warren 01/06/2020 Pediatric blood & cancer
M Qayed, T Cash, M Tighiouart, TJ MacDonald, KC Goldsmith, R Tanos, L Kean, B Watkins, Y Suessmuth, C Wetmore, HM Katzenstein 01/04/2020 Nature communications
SI Ahn, YJ Sei, HJ Park, J Kim, Y Ryu, JJ Choi, HJ Sung, TJ MacDonald, AI Levey, Y Kim 10/01/2020 Translational oncology
BI Siegel, TZ King, M Rupji, B Dwivedi, AB Carter, J Kowalski, TJ MacDonald 01/07/2019 Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma.
Nature communications
V Maximov, Z Chen, Y Wei, MH Robinson, CJ Herting, NS Shanmugam, VA Rudneva, KC Goldsmith, TJ MacDonald, PA Northcott, D Hambardzumyan, AM Kenney 03/06/2019 Three-Dimensional Mass Spectrometry Imaging Identifies Lipid Markers of Medulloblastoma Metastasis.
Scientific reports
MRL Paine, J Liu, D Huang, SR Ellis, D Trede, JH Kobarg, RMA Heeren, FM Fernández, TJ MacDonald 18/02/2019 Science signaling
THW Dobson, RH Tao, J Swaminathan, S Maegawa, S Shaik, J Bravo-Alegria, A Sharma, B Kennis, Y Yang, K Callegari, AR Haltom, P Taylor, M Kogiso, L Qi, S Khatua, S Goldman, RR Lulla, J Fangusaro, TJ MacDonald, XN Li, C Hawkins, V Rajaram, V Gopalakrishnan 22/01/2019 Rapid discrimination of pediatric brain tumors by mass spectrometry imaging.
Journal of neuro-oncology
AR Clark, D Calligaris, MS Regan, D Pomeranz Krummel, JN Agar, L Kallay, T MacDonald, M Schniederjan, S Santagata, SL Pomeroy, NYR Agar, S Sengupta 01/11/2018 Neuro-oncology
N Gupta, LC Goumnerova, P Manley, SN Chi, D Neuberg, M Puligandla, J Fangusaro, S Goldman, T Tomita, T Alden, A DiPatri, JB Rubin, K Gauvain, D Limbrick, J Leonard, JR Geyer, S Leary, S Browd, Z Wang, S Sood, A Bendel, M Nagib, S Gardner, MA Karajannis, D Harter, K Ayyanar, W Gump, DC Bowers, B Weprin, TJ MacDonald, D Aguilera, B Brahma, NJ Robison, E Kiehna, M Krieger, E Sandler, P Aldana, Z Khatib, J Ragheb, S Bhatia, S Mueller, A Banerjee, AL Bredlau, S Gururangan, H Fuchs, KJ Cohen, G Jallo, K Dorris, M Handler, M Comito, M Dias, K Nazemi, L Baird, J Murray, N Lindeman, JL Hornick, H Malkin, C Sinai, L Greenspan, KD Wright, M Prados, P Bandopadhayay, KL Ligon, MW Kieran 09/10/2018 BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Cancer cell
D Zhu, S Osuka, Z Zhang, ZR Reichert, L Yang, Y Kanemura, Y Jiang, S You, H Zhang, NS Devi, D Bhattacharya, S Takano, GY Gillespie, T Macdonald, C Tan, R Nishikawa, WG Nelson, JJ Olson, EG Van Meir 11/06/2018 The Lancet. Oncology
SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, S Groebner, KB Grund, L Brugières, DTW Jones, KW Pajtler, AS Morrissy, M Kool, D Sturm, L Chavez, A Ernst, S Brabetz, M Hain, T Zichner, M Segura-Wang, J Weischenfeldt, T Rausch, BR Mardin, X Zhou, C Baciu, C Lawerenz, JA Chan, P Varlet, L Guerrini-Rousseau, DW Fults, W Grajkowska, P Hauser, N Jabado, YS Ra, K Zitterbart, SS Shringarpure, FM De La Vega, CD Bustamante, HK Ng, A Perry, TJ MacDonald, P Hernáiz Driever, AE Bendel, DC Bowers, G McCowage, MM Chintagumpala, R Cohn, T Hassall, G Fleischhack, T Eggen, F Wesenberg, M Feychting, B Lannering, J Schüz, C Johansen, TV Andersen, M Röösli, CE Kuehni, M Grotzer, K Kjaerheim, CM Monoranu, TC Archer, E Duke, SL Pomeroy, R Shelagh, S Frank, D Sumerauer, W Scheurlen, MV Ryzhova, T Milde, CP Kratz, D Samuel, J Zhang, DA Solomon, M Marra, R Eils, CR Bartram, K von Hoff, S Rutkowski, V Ramaswamy, RJ Gilbertson, A Korshunov, MD Taylor, P Lichter, D Malkin, A Gajjar, JO Korbel, SM Pfister 01/06/2018 Clinical responses of patients with diffuse leptomeningeal glioneuronal tumors to chemotherapy.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
D Aguilera, RC Castellino, A Janss, M Schniederjan, R McNall, T MacDonald, C Mazewski 01/02/2018 NeuroImage. Clinical
S Na, L Li, B Crosson, V Dotson, TJ MacDonald, H Mao, TZ King 01/01/2018 Pediatric blood & cancer
ME Macy, MW Kieran, SN Chi, KJ Cohen, TJ MacDonald, AA Smith, MM Etzl, MC Kuei, AM Donson, L Gore, J DiRenzo, TM Trippett, I Ostrovnaya, A Narendran, NK Foreman, IJ Dunkel 01/11/2017 Neuro-oncology
MW Kieran, J Chisholm, M Casanova, AA Brandes, I Aerts, E Bouffet, S Bailey, S Leary, TJ MacDonald, F Mechinaud, KJ Cohen, R Riccardi, W Mason, D Hargrave, S Kalambakas, P Deshpande, F Tai, E Hurh, B Geoerger 19/10/2017 Colloids and surfaces. B, Biointerfaces
R Lin, Y Li, T MacDonald, H Wu, J Provenzale, X Peng, J Huang, L Wang, AY Wang, J Yang, H Mao 01/02/2017 Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma.
Neuro-oncology
BR Eaton, N Esiashvili, S Kim, B Patterson, EA Weyman, LT Thornton, C Mazewski, TJ MacDonald, D Ebb, SM MacDonald, NJ Tarbell, TI Yock 01/06/2016 Successful Retreatment of a Child with a Refractory Brainstem Ganglioglioma with Vemurafenib.
Pediatric blood & cancer
D Aguilera, A Janss, C Mazewski, RC Castellino, M Schniederjan, L Hayes, B Brahma, L Fogelgren, TJ MacDonald 01/03/2016 Divergent clonal selection dominates medulloblastoma at recurrence.
Nature
AS Morrissy, L Garzia, DJ Shih, S Zuyderduyn, X Huang, P Skowron, M Remke, FM Cavalli, V Ramaswamy, PE Lindsay, S Jelveh, LK Donovan, X Wang, B Luu, K Zayne, Y Li, C Mayoh, N Thiessen, E Mercier, KL Mungall, Y Ma, K Tse, T Zeng, K Shumansky, AJ Roth, S Shah, H Farooq, N Kijima, BL Holgado, JJ Lee, S Matan-Lithwick, J Liu, SC Mack, A Manno, KA Michealraj, C Nor, J Peacock, L Qin, J Reimand, A Rolider, YY Thompson, X Wu, T Pugh, A Ally, M Bilenky, YS Butterfield, R Carlsen, Y Cheng, E Chuah, RD Corbett, N Dhalla, A He, D Lee, HI Li, W Long, M Mayo, P Plettner, JQ Qian, JE Schein, A Tam, T Wong, I Birol, Y Zhao, CC Faria, J Pimentel, S Nunes, T Shalaby, M Grotzer, IF Pollack, RL Hamilton, XN Li, AE Bendel, DW Fults, AW Walter, T Kumabe, T Tominaga, VP Collins, YJ Cho, C Hoffman, D Lyden, JH Wisoff, JH Garvin, DS Stearns, L Massimi, U Schüller, J Sterba, K Zitterbart, S Puget, O Ayrault, SE Dunn, DP Tirapelli, CG Carlotti, H Wheeler, AR Hallahan, W Ingram, TJ MacDonald, JJ Olson, EG Van Meir, JY Lee, KC Wang, SK Kim, BK Cho, T Pietsch, G Fleischhack, S Tippelt, YS Ra, S Bailey, JC Lindsey, SC Clifford, CG Eberhart, MK Cooper, RJ Packer, M Massimino, ML Garre, U Bartels, U Tabori, CE Hawkins, P Dirks, E Bouffet, JT Rutka, RJ Wechsler-Reya, WA Weiss, LS Collier, AJ Dupuy, A Korshunov, DT Jones, M Kool, PA Northcott, SM Pfister, DA Largaespada, AJ Mungall, RA Moore, N Jabado, GD Bader, SJ Jones, D Malkin, MA Marra, MD Taylor 21/01/2016 International journal of radiation oncology, biology, physics
BR Eaton, N Esiashvili, S Kim, EA Weyman, LT Thornton, C Mazewski, T MacDonald, D Ebb, SM MacDonald, NJ Tarbell, TI Yock 01/01/2016 The emerging role of NG2 in pediatric diffuse intrinsic pontine glioma.
Oncotarget
S Yadavilli, J Scafidi, OJ Becher, AM Saratsis, RL Hiner, M Kambhampati, S Mariarita, TJ MacDonald, KE Codispoti, SN Magge, JK Jaiswal, RJ Packer, J Nazarian 20/05/2015 Journal of materials chemistry. B
Y Li, R Lin, L Wang, J Huang, H Wu, G Cheng, Z Zhou, T MacDonald, L Yang, H Mao 07/05/2015 Oncotarget
S Bhatia, NA Baig, O Timofeeva, EB Pasquale, K Hirsch, TJ MacDonald, A Dritschilo, YC Lee, M Henkemeyer, B Rood, M Jung, XJ Wang, M Kool, O Rodriguez, C Albanese, SD Karam 20/04/2015 Clinical cancer research : an official journal of the American Association for Cancer Research
Y Shou, DM Robinson, DD Amakye, KL Rose, YJ Cho, KL Ligon, T Sharp, AS Haider, R Bandaru, Y Ando, B Geoerger, F Doz, DM Ashley, DR Hargrave, M Casanova, HA Tawbi, J Rodon, AL Thomas, AC Mita, TJ MacDonald, MW Kieran 01/02/2015 EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma.
Journal of neuro-oncology
N McKinney, L Yuan, H Zhang, J Liu, YJ Cho, E Rushing, M Schniederjan, TJ MacDonald 01/01/2015 Cancer letters
W Petersen, J Liu, L Yuan, H Zhang, M Schneiderjan, YJ Cho, TJ MacDonald 01/11/2014 Response of subependymal giant cell astrocytoma with spinal cord metastasis to everolimus.
Journal of pediatric hematology/oncology
D Aguilera, R Flamini, C Mazewski, M Schniederjan, L Hayes, W Boydston, RC Castellino, TJ MacDonald 01/10/2014 Journal of pediatric hematology/oncology
LL Hartman, JR Crawford, MT Makale, M Milburn, S Joshi, AM Salazar, B Hasenauer, SR VandenBerg, TJ MacDonald, DL Durden 01/08/2014 Nature materials
A Jain, M Betancur, GD Patel, CM Valmikinathan, VJ Mukhatyar, A Vakharia, SB Pai, B Brahma, TJ MacDonald, RV Bellamkonda 01/03/2014 Acta neuropathologica
AM Saratsis, M Kambhampati, K Snyder, S Yadavilli, JM Devaney, B Harmon, J Hall, EH Raabe, P An, M Weingart, BR Rood, SN Magge, TJ MacDonald, RJ Packer, J Nazarian 01/01/2014 Journal for immunotherapy of cancer
M Li, AR Bolduc, MN Hoda, DN Gamble, SB Dolisca, AK Bolduc, K Hoang, C Ashley, D McCall, AM Rojiani, BL Maria, O Rixe, TJ MacDonald, PS Heeger, AL Mellor, DH Munn, TS Johnson 01/01/2014 The rationale for targeted therapies in medulloblastoma.
Neuro-oncology
TJ MacDonald, D Aguilera, RC Castellino 01/01/2014 Neuro-oncology
TJ MacDonald, G Vezina, CF Stewart, D Turner, CR Pierson, L Chen, IF Pollack, A Gajjar, MW Kieran 01/10/2013 Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
D Aguilera, C Mazewski, J Fangusaro, TJ MacDonald, RY McNall-Knapp, LL Hayes, S Kim, RC Castellino 01/04/2013 Molecular cancer
L Yuan, H Zhang, J Liu, JB Rubin, YJ Cho, HK Shu, M Schniederjan, TJ MacDonald 05/03/2013 Journal of pediatric hematology/oncology
DG Aguilera, C Mazewski, L Hayes, C Jordan, N Esiashivilli, A Janns, TJ Macdonald 01/01/2013 Pediatric blood & cancer
M Yalon, B Rood, TJ MacDonald, G McCowage, R Kane, S Constantini, RJ Packer 01/01/2013 Journal of neuro-oncology
Z Shi, N Esiashvili, AJ Janss, CM Mazewski, TJ MacDonald, DM Wrubel, B Brahma, FP Schwaibold, RB Marcus, IR Crocker, HK Shu 01/09/2012 REST is a novel prognostic factor and therapeutic target for medulloblastoma.
Molecular cancer therapeutics
P Taylor, J Fangusaro, V Rajaram, S Goldman, IB Helenowski, T MacDonald, M Hasselblatt, L Riedemann, A Laureano, L Cooper, V Gopalakrishnan 01/08/2012 Diffuse intrinsic pontine glioma (DIPG): time to biopsy again?
Pediatric blood & cancer
TJ MacDonald 01/04/2012 Clonal selection drives genetic divergence of metastatic medulloblastoma.
Nature
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJ Shih, H Witt, S Croul, E Bouffet, DW Fults, CG Eberhart, L Garzia, T Van Meter, D Zagzag, N Jabado, J Schwartzentruber, J Majewski, TE Scheetz, SM Pfister, A Korshunov, XN Li, SW Scherer, YJ Cho, K Akagi, TJ MacDonald, J Koster, MG McCabe, AL Sarver, VP Collins, WA Weiss, DA Largaespada, LS Collier, MD Taylor 15/02/2012 Hedgehog Pathway in Pediatric Cancers: They're Not Just for Brain Tumors Anymore.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
TJ Macdonald 01/01/2012 Cancer biology & therapy
L Ringer, P Sirajuddin, M Heckler, A Ghosh, F Suprynowicz, VM Yenugonda, ML Brown, JA Toretsky, A Uren, Y Lee, TJ MacDonald, O Rodriguez, RI Glazer, R Schlegel, C Albanese 01/11/2011 Treatment of high-grade glioma in children and adolescents.
Neuro-oncology
TJ MacDonald, D Aguilera, CM Kramm 01/10/2011 A MCP1 fusokine with CCR2-specific tumoricidal activity.
Molecular cancer
M Rafei, J Deng, MN Boivin, P Williams, SM Matulis, S Yuan, E Birman, K Forner, L Yuan, C Castellino, LH Boise, TJ MacDonald, J Galipeau 24/09/2011 Identification of transcriptional regulatory networks specific to pilocytic astrocytoma.
BMC medical genomics
H Deshmukh, J Yu, J Shaik, TJ MacDonald, A Perry, JE Payton, DH Gutmann, MA Watson, R Nagarajan 11/07/2011 Secretome signature of invasive glioblastoma multiforme.
Journal of proteome research
CA Formolo, R Williams, H Gordish-Dressman, TJ MacDonald, NH Lee, Y Hathout 01/07/2011 Characterization of signaling function and expression of HLA class I molecules in medulloblastoma.
Journal of neuro-oncology
C Smith, M Santi, EJ Rushing, R Cornelison, TJ MacDonald, S Vukmanovic 01/06/2011 Neurofibromatosis-2 and spinal cord ependymomas: Report of two cases and review of the literature.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
DG Aguilera, C Mazewski, MJ Schniederjan, T Leong, W Boydston, TJ Macdonald 01/05/2011 Proteomics
MU Rajagopal, Y Hathout, TJ MacDonald, MW Kieran, S Gururangan, SM Blaney, P Phillips, R Packer, H Gordish-Dressman, BR Rood 01/03/2011 Journal of neuro-oncology
TJ Abouantoun, RC Castellino, TJ MacDonald 01/01/2011 The Journal of clinical investigation
EM Beauchamp, L Ringer, G Bulut, KP Sajwan, MD Hall, YC Lee, D Peaceman, M Ozdemirli, O Rodriguez, TJ Macdonald, C Albanese, JA Toretsky, A Uren 01/01/2011 ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration.
Clinical & experimental metastasis
L Yuan, M Santi, EJ Rushing, R Cornelison, TJ MacDonald 01/10/2010 Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.
PloS one
RC Castellino, BG Barwick, M Schniederjan, MC Buss, O Becher, D Hambardzumyan, TJ Macdonald, DJ Brat, DL Durden 26/05/2010 Cancer research
OJ Becher, D Hambardzumyan, TR Walker, K Helmy, J Nazarian, S Albrecht, RL Hiner, S Gall, JT Huse, N Jabado, TJ MacDonald, EC Holland 15/03/2010 Central nervous system tumors.
Hematology/oncology clinics of North America
RJ Packer, T Macdonald, G Vezina 01/02/2010 Journal of neuro-oncology
JR Crawford, MR Santi, R Cornelison, SL Sallinen, H Haapasalo, TJ MacDonald 01/10/2009 Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
JR Crawford, MR Santi, HK Thorarinsdottir, R Cornelison, EJ Rushing, H Zhang, K Yao, S Jacobson, TJ Macdonald 01/09/2009 A novel role of HLA class I in the pathology of medulloblastoma.
Journal of translational medicine
C Smith, M Santi, B Rajan, EJ Rushing, MR Choi, BR Rood, R Cornelison, TJ MacDonald, S Vukmanovic 12/07/2009 Molecular cancer therapeutics
TJ Abouantoun, TJ MacDonald 01/05/2009 Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival.
Pediatric blood & cancer
K Chen, S Fallen, HO Abaan, M Hayran, C Gonzalez, F Wodajo, T MacDonald, JA Toretsky, A Uren 01/09/2008 Journal of clinical oncology : official journal of the American Society of Clinical Oncology
TJ MacDonald, CF Stewart, M Kocak, S Goldman, RG Ellenbogen, P Phillips, D Lafond, TY Poussaint, MW Kieran, JM Boyett, LE Kun 20/02/2008