Bo Liang, PhD
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Research Program
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Phone Number
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Email Address
Biography
Bo Liang, PhD, is an associate professor in the Department of Biochemistry at Emory University School of Medicine. Dr. Liang also serves as co-scientific adviser of the Robert P. Apkarian Integrated Electron Microscopy Core (IEMC) at Emory University.
Dr. Liang is a member of the Discovery and Developmental Therapeutics Research Program at Winship Cancer Institute.
Education
Dr. Liang received his PhD in Molecular Biophysics from Florida State University in Tallahassee, Florida. He then completed a postdoctoral fellowship in Structural Cell Biology and Microbiology at Harvard Medical School in Boston, Massachusetts.
Titles & Roles
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Associate Professor, Department of BiochemistryEmory University School of Medicine
Research
Dr. Liang's research interest focuses on the integrated approaches of cryo-electron microscopy (cryo-EM), x-ray crystallography and fluorescence light microscopy to uncover the molecular mechanisms of human disease associated macromolecular machineries. He is also interested in sampling and deciphering the structural and dynamic aspects of molecules that are critical for their biological function in real time at single molecule level.
| Title/Journal | Authors | Publication Date |
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Structures of the promoter-bound respiratory syncytial virus polymerase. Nature |
D Cao, Y Gao, Z Chen, I Gooneratne, C Roesler, C Mera, P D'Cunha, A Antonova, D Katta, S Romanelli, Q Wang, S Rice, W Lemons, A Ramanathan, B Liang | 01/01/2024 |
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Journal of medical virology |
H Ahn, BM Calderon, X Fan, Y Gao, NL Horgan, N Jiang, DS Blohm, J Hossain, NWK Rayyan, SH Osman, X Lin, M Currier, J Steel, DE Wentworth, B Zhou, B Liang | 01/10/2023 |
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Microorganisms |
E Xu, S Park, J Calderon, D Cao, B Liang | 18/06/2023 |
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Pediatric neurology |
C Ocampo-Chih, H Dennis, N Lall, N Pham, B Liang, S Verma, J Neira Fresneda | 01/02/2023 |
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Optimal Conditions for In Vitro Assembly of Respiratory Syncytial Virus Nucleocapsid-like Particles. Viruses |
Y Gao, A Raghavan, B Deng, J Lee, B Liang | 25/01/2023 |
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The Journal of infectious diseases |
MK Roe, MA Perez, HM Hsiao, SA Lapp, HY Sun, S Jadhao, AR Young, YS Batista, RC Reed, A Taz, A Piantadosi, X Chen, B Liang, M Koval, TA Snider, ML Moore, EJ Anderson, LJ Anderson, CC Stobart, CA Rostad | 28/12/2022 |
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Analysis of Template Variations on RNA Synthesis by Respiratory Syncytial Virus Polymerase. Viruses |
D Cao, I Gooneratne, C Mera, J Vy, M Royal, B Huang, Y Park, A Manjunath, B Liang | 23/12/2022 |
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Scientific reports |
W Wu, JS Kim, AO Bailey, WK Russell, SJ Richards, T Chen, T Chen, Z Chen, B Liang, M Yamauchi, H Guo | 07/10/2022 |
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Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer. Bioorganic & medicinal chemistry |
X Yang, D Fan, AH Troha, HM Ahn, K Qian, B Liang, Y Du, H Fu, AA Ivanov | 01/09/2021 |
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Generation and Assembly of Virus-Specific Nucleocapsids of the Respiratory Syncytial Virus. Journal of visualized experiments : JoVE |
Y Gao, C Ogilvie, A Raghavan, C Von Hoffmann, B Liang | 27/07/2021 |
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The basis of a more contagious 501Y.V1 variant of SARS-CoV-2. Cell research |
H Liu, Q Zhang, P Wei, Z Chen, K Aviszus, J Yang, W Downing, C Jiang, B Liang, L Reynoso, GP Downey, SK Frankel, J Kappler, P Marrack, G Zhang | 01/06/2021 |
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Structural Insights into the Respiratory Syncytial Virus RNA Synthesis Complexes. Viruses |
D Cao, Y Gao, B Liang | 05/05/2021 |
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Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase. Microorganisms |
K Zandi, K Musall, A Oo, D Cao, B Liang, P Hassandarvish, S Lan, RL Slack, KA Kirby, L Bassit, F Amblard, B Kim, S AbuBakar, SG Sarafianos, RF Schinazi | 22/04/2021 |
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STAR protocols |
Y Gao, D Cao, S Pawnikar, S Akhter, Y Miao, B Liang | 19/03/2021 |
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Cryo-Electron Microscopy Structures of the Pneumoviridae Polymerases. Viral immunology |
D Cao, B Liang | 01/01/2021 |
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Repurposing Nucleoside Analogs for Human Coronaviruses. Antimicrobial agents and chemotherapy |
K Zandi, F Amblard, K Musall, J Downs-Bowen, R Kleinbard, A Oo, D Cao, B Liang, OO Russell, T McBrayer, L Bassit, B Kim, RF Schinazi | 16/12/2020 |
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In Vitro Primer-Based RNA Elongation and Promoter Fine Mapping of the Respiratory Syncytial Virus. Journal of virology |
D Cao, Y Gao, C Roesler, S Rice, P D'Cunha, L Zhuang, J Slack, A Antonova, S Romanelli, B Liang | 09/12/2020 |
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Structures of the Mononegavirales Polymerases. Journal of virology |
B Liang | 27/10/2020 |
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Structure (London, England : 1993) |
Y Gao, D Cao, S Pawnikar, KP John, HM Ahn, S Hill, JM Ha, P Parikh, C Ogilvie, A Swain, A Yang, A Bell, A Salazar, Y Miao, B Liang | 01/09/2020 |
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Cryo-EM structure of the respiratory syncytial virus RNA polymerase. Nature communications |
D Cao, Y Gao, C Roesler, S Rice, P D'Cunha, L Zhuang, J Slack, M Domke, A Antonova, S Romanelli, S Keating, G Forero, P Juneja, B Liang | 17/01/2020 |
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In vitro trackable assembly of RNA-specific nucleocapsids of the respiratory syncytial virus. The Journal of biological chemistry |
Y Gao, D Cao, HM Ahn, A Swain, S Hill, C Ogilvie, M Kurien, T Rahmatullah, B Liang | 17/01/2020 |
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Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. Cell reports |
S Jenni, LM Bloyet, R Diaz-Avalos, B Liang, SPJ Whelan, N Grigorieff, SC Harrison | 07/01/2020 |
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Virology |
JF Trost, W Wang, B Liang, SE Galloway, E Agbogu, L Byrd-Leotis, DA Steinhauer | 01/10/2019 |
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Science advances |
J Duan, J Li, GL Chen, Y Ge, J Liu, K Xie, X Peng, W Zhou, J Zhong, Y Zhang, J Xu, C Xue, B Liang, L Zhu, W Liu, C Zhang, XL Tian, J Wang, DE Clapham, B Zeng, Z Li, J Zhang | 01/07/2019 |