Peng Jin, PhD
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Research Program
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Phone Number
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Email Address
Biography
Education
Dr. Peng Jin received his doctorate degree in Molecular and Developmental Biology from Cincinnati Children’s Hospital/University of Cincinnati and completed postdoctoral training at Emory University.
Titles & Roles
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Professor and Chair, Department of Human GeneticsEmory University School of Medicine
Research
Dr. Jin's research philosophy combines various disciplines (biochemistry, genetics, chemistry, human genetics/genomics, and bioinformatics) to understand the functions and mechanisms of epigenetics and noncoding RNAs in neurodevelopmental and neurodegenerative disorders.
Grants
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Grant Number Title 1P50HD104458-01 Administrative Core 1P50HD104458-01 FMRP-mediated Regulation in Human Brain Development and Therapeutic Advancement 1R35NS111602-01 Dynamic DNA Modifications in Brain and Diseases 5P50HD104458-02 Administrative Core 5P50HD104458-02 FMRP-mediated Regulation in Human Brain Development and Therapeutic Advancement 5P50HD104458-03 Administrative Core 5P50HD104458-03 FMRP-mediated Regulation in Human Brain Development and Therapeutic Advancement 5P50HD104458-04 FMRP-mediated Regulation in Human Brain Development and Therapeutic Advancement 5R35NS111602-02 Dynamic DNA Modifications in Brain and Diseases 5R35NS111602-03 Dynamic DNA Modifications in Brain and Diseases 5R35NS111602-04 Dynamic DNA Modifications in Brain and Diseases 5R35NS111602-05 Dynamic DNA Modifications in Brain and Diseases Publications
Dr. Jin is the recipient of Beckman Young Investigator Award, Basil O'Connor Scholar Research Award, Alfred P. Sloan Research Fellow in Neuroscience, and NARSAD Independent Investigator Award.
Title/Journal Authors Publication Date Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases.
Epigenomics
KR Westover, P Jin, B Yao 26/03/2024 bioRxiv : the preprint server for biology
X Ma, SR Thela, F Zhao, B Yao, Z Wen, P Jin, J Zhao, L Chen 06/03/2024 Characterization and visualization of tandem repeats at genome scale.
Nature biotechnology
E Dolzhenko, A English, H Dashnow, G De Sena Brandine, T Mokveld, WJ Rowell, C Karniski, Z Kronenberg, MC Danzi, WA Cheung, C Bi, E Farrow, A Wenger, KP Chua, V Martínez-Cerdeño, TD Bartley, P Jin, DL Nelson, S Zuchner, T Pastinen, AR Quinlan, FJ Sedlazeck, MA Eberle 02/01/2024 Epigenetic modifications of DNA and RNA in Alzheimer's disease.
Frontiers in molecular neuroscience
P Martinez-Feduchi, P Jin, B Yao 01/01/2024 BMC medicine
J Ye, Z Huang, Q Li, Z Li, Y Lan, Z Wang, C Ni, X Wu, T Jiang, Y Li, Q Yang, J Lim, CY Ren, M Jiang, S Li, P Jin, JH Chen, C Zhao 12/12/2023 FMRP phosphorylation modulates neuronal translation through YTHDF1.
Molecular cell
Z Zou, J Wei, Y Chen, Y Kang, H Shi, F Yang, Z Shi, S Chen, Y Zhou, C Sepich-Poore, X Zhuang, X Zhou, H Jiang, Z Wen, P Jin, C Luo, C He 07/12/2023 Molecular neurobiology
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo 22/11/2023 Cells
F Tassone, D Protic, EG Allen, AD Archibald, A Baud, TW Brown, DB Budimirovic, J Cohen, B Dufour, R Eiges, N Elvassore, LV Gabis, SJ Grudzien, DA Hall, D Hessl, A Hogan, JE Hunter, P Jin, P Jiraanont, J Klusek, RF Kooy, CM Kraan, C Laterza, A Lee, K Lipworth, M Losh, D Loesch, R Lozano, MR Mailick, A Manolopoulos, V Martinez-Cerdeno, Y McLennan, RM Miller, FAM Montanaro, MW Mosconi, SN Potter, M Raspa, SM Rivera, K Shelly, PK Todd, K Tutak, JY Wang, A Wheeler, TI Winarni, M Zafarullah, RJ Hagerman 21/09/2023 Role of TET1-mediated epigenetic modulation in Alzheimer's disease.
Neurobiology of disease
MJ Armstrong, Y Jin, SM Vattathil, Y Huang, JP Schroeder, DA Bennet, ZS Qin, TS Wingo, P Jin 01/09/2023 Research square
Z Mei, J Liu, JP Schroeder, D Weinshenker, DM Duong, NT Seyfried, Y Li, P Jin, AP Wingo, TS Wingo 16/08/2023 Molecular neurobiology
L Lin, X Liu, X Cheng, Y Li, M Gearing, A Levey, X Huang, Y Li, P Jin, X Li 01/05/2023 Alzheimer's & dementia : the journal of the Alzheimer's Association
H Palma-Gudiel, L Yu, Z Huo, J Yang, Y Wang, T Gu, C Gao, PL De Jager, P Jin, DA Bennett, J Zhao 01/04/2023 bioRxiv : the preprint server for biology
S Sharma, W Ma, KJ Ressler, T Anderson, DC Li, P Jin, SL Gourley, Z Qin 10/03/2023 Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice.
The Journal of clinical investigation
W Ding, L Fischer, Q Chen, Z Li, L Yang, Z You, K Hu, X Wu, X Zhou, W Chao, P Hu, TM Dagnew, DM Dubreuil, S Wang, S Xia, C Bao, S Zhu, L Chen, C Wang, B Wainger, P Jin, J Mao, G Feng, MT Harnett, S Shen 01/03/2023 Age-Dependent Dysregulation of APP in Neuronal and Skin Cells from Fragile X Individuals.
Cells
G Cencelli, L Pacini, A De Luca, I Messia, A Gentile, Y Kang, V Nobile, E Tabolacci, P Jin, MG Farace, C Bagni 27/02/2023 bioRxiv : the preprint server for biology
HV Wang, AM Veire, TF Gendron, M Gearing, JD Glass, P Jin, VG Corces, ZT McEachin 13/01/2023 Human molecular genetics
Y Jin, K Su, HE Kong, W Ma, Z Wang, Y Li, R Li, EG Allen, H Wu, P Jin 06/01/2023 Frontiers in genetics
R Satange, P Jin, MH Hou, AB Rode 01/01/2023 Analyzing mRNA Epigenetic Sequencing Data with TRESS.
Methods in molecular biology (Clifton, N.J.)
Z Guo, AM Shafik, P Jin, Z Wu, H Wu 01/01/2023 Proceedings of the National Academy of Sciences of the United States of America
YH Jung, HV Wang, D Ruiz, BJ Bixler, H Linsenbaum, JF Xiang, S Forestier, AM Shafik, P Jin, VG Corces 13/12/2022 Science advances
Q Liu, K Zhang, Y Kang, Y Li, P Deng, Y Li, Y Tian, Q Sun, Y Tang, K Xu, Y Zhou, JL Wang, J Guo, JD Li, K Xia, Q Meng, EG Allen, Z Wen, Z Li, H Jiang, L Shen, R Duan, B Yao, B Tang, P Jin, Y Pan 25/11/2022 Differential RNA methylation analysis for MeRIP-seq data under general experimental design.
Bioinformatics (Oxford, England)
Z Guo, AM Shafik, P Jin, H Wu 14/10/2022 Altered hydroxymethylome in the substantia nigra of Parkinson's disease.
Human molecular genetics
S Min, Q Xu, L Qin, Y Li, Z Li, C Chen, H Wu, J Han, X Zhu, P Jin, B Tang 10/10/2022 Epitranscriptomic dynamics in brain development and disease.
Molecular psychiatry
AM Shafik, EG Allen, P Jin 01/09/2022 American journal of medical genetics. Part A
JV Reyes Diaz, Y Jin, K Garber, KM Cossen, Y Li, P Jin, H Li, JN Ham 01/08/2022 Descriptive analysis of seizures and comorbidities associated with fragile X syndrome.
Molecular genetics & genomic medicine
I Albizua, K Charen, L Shubeck, A Talboy, E Berry-Kravis, WE Kaufmann, JL Stallworth, KT Drazba, CA Erickson, JA Sweeney, N Tartaglia, SF Warren, R Hagerman, SL Sherman, ST Warren, P Jin, EG Allen 01/08/2022 Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome.
Proceedings of the National Academy of Sciences of the United States of America
HE Kong, J Lim, A Linsalata, Y Kang, I Malik, EG Allen, Y Cao, L Shubeck, R Johnston, Y Huang, Y Gu, X Guo, ME Zwick, Z Qin, TS Wingo, J Juncos, DL Nelson, MP Epstein, DJ Cutler, PK Todd, SL Sherman, ST Warren, P Jin 31/05/2022 Across Dimensions: Developing 2D and 3D Human iPSC-Based Models of Fragile X Syndrome.
Cells
A Lee, J Xu, Z Wen, P Jin 24/05/2022 Dysregulated mitochondrial and cytosolic tRNA m1A methylation in Alzheimer's disease.
Human molecular genetics
AM Shafik, H Zhou, J Lim, B Dickinson, P Jin 19/05/2022 Briefings in bioinformatics
W Ma, S Sharma, P Jin, SL Gourley, ZS Qin 13/05/2022 Cell-free DNA methylation as a potential biomarker in brain disorders.
Epigenomics
Y Jin, EG Allen, P Jin 01/04/2022 Journal of personalized medicine
J Deng, XX Guan, YB Zhu, HT Deng, GX Li, YC Guo, P Jin, RH Duan, W Huang 02/03/2022 Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
Translational psychiatry
AP Wingo, M Wang, J Liu, MS Breen, HS Yang, B Tang, JA Schneider, NT Seyfried, JJ Lah, AI Levey, DA Bennett, P Jin, PL De Jager, TS Wingo 01/02/2022 Disease category-specific annotation of variants using an ensemble learning framework.
Briefings in bioinformatics
Z Cao, Y Huang, R Duan, P Jin, ZS Qin, S Zhang 17/01/2022 Stephen T. Warren, Ph.D. (1953-2021): A remembrance.
American journal of human genetics
DL Nelson, J Clark, K Garber, T Glover, T Hassold, P Jin, HT Orr, SL Sherman, H Zoghbi, KL Warren 06/01/2022 Molecular neurobiology
XR Huang, BS Tang, P Jin, JF Guo 01/01/2022 Stress modulates Ahi1-dependent nuclear localization of ten-eleven translocation protein 2.
Human molecular genetics
Q Zhang, Q Hu, J Wang, Z Miao, Z Li, Y Zhao, B Wan, EG Allen, M Sun, P Jin, X Xu 01/11/2021 Human molecular genetics
C Meng, L Gu, Y Li, R Li, Y Cao, Z Li, EG Allen, D Zhu, P Jin 13/10/2021 Nature neuroscience
Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen 01/10/2021 Remembering Stephen T. Warren, a pillar of neurogenetics (1953-2021).
Nature neuroscience
P Jin, GJ Bassell 01/10/2021 Detecting m6A methylation regions from Methylated RNA Immunoprecipitation Sequencing.
Bioinformatics (Oxford, England)
Z Guo, AM Shafik, P Jin, Z Wu, H Wu 29/09/2021 Nucleic acids research
CR Jhan, R Satange, SC Wang, JY Zeng, YC Horng, P Jin, S Neidle, MH Hou 20/09/2021 Fertility and sterility
CE Trevino, JC Rounds, K Charen, L Shubeck, HS Hipp, JB Spencer, HR Johnston, DJ Cutler, ME Zwick, MP Epstein, A Murray, JN Macpherson, M Mila, L Rodriguez-Revenga, E Berry-Kravis, DA Hall, MA Leehey, Y Liu, C Welt, ST Warren, SL Sherman, P Jin, EG Allen 01/09/2021 Nature communications
Y Huang, X Sun, H Jiang, S Yu, C Robins, MJ Armstrong, R Li, Z Mei, X Shi, ES Gerasimov, PL De Jager, DA Bennett, AP Wingo, P Jin, TS Wingo, ZS Qin 22/07/2021 Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats.
Human molecular genetics
B Jiao, M Wang, H Feng, H Bao, F Zhang, H Wu, J Wang, B Tang, P Jin, L Shen 29/05/2021 Human molecular genetics
KE Shelly, NR Candelaria, Z Li, EG Allen, P Jin, DL Nelson 29/05/2021 Important Correlates of Purpose in Life Identified Through a Machine Learning Approach.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Z Mei, A Lori, SM Vattathil, PA Boyle, B Bradley, P Jin, DA Bennett, TS Wingo, AP Wingo 01/05/2021 Ten-eleven translocation protein 1 modulates medulloblastoma progression.
Genome biology
H Kim, Y Kang, Y Li, L Chen, L Lin, ND Johnson, D Zhu, MH Robinson, L McSwain, BG Barwick, X Yuan, X Liao, J Zhao, Z Zhang, Q Shu, J Chen, EG Allen, AM Kenney, RC Castellino, EG Van Meir, KN Conneely, PM Vertino, P Jin, J Li 29/04/2021 Cell reports
N Raj, ZT McEachin, W Harousseau, Y Zhou, F Zhang, ME Merritt-Garza, JM Taliaferro, M Kalinowska, SG Marro, CM Hales, E Berry-Kravis, MW Wolf-Ochoa, V Martinez-Cerdeño, M Wernig, L Chen, E Klann, ST Warren, P Jin, Z Wen, GJ Bassell 13/04/2021 Nature communications
G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu 23/02/2021 Nature communications
G Song, G Wang, X Luo, Y Cheng, Q Song, J Wan, C Moore, H Song, P Jin, J Qian, H Zhu 04/02/2021 Genome biology
AM Shafik, F Zhang, Z Guo, Q Dai, K Pajdzik, Y Li, Y Kang, B Yao, H Wu, C He, EG Allen, R Duan, P Jin 05/01/2021 Frontiers in cell and developmental biology
W Ren, C Xu, FJ Zheng, TT Lin, P Jin, Y Zhang, WW Guo, CH Liu, XY Zhou, LL Wang, Y Wang, H Zhao, SM Yang 01/01/2021 Therapeutic Development for CGG Repeat Expansion-Associated Neurodegeneration.
Frontiers in cellular neuroscience
K Xu, Y Li, EG Allen, P Jin 01/01/2021 Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells.
Neuron
B Asrican, J Wooten, YD Li, L Quintanilla, F Zhang, C Wander, H Bao, CY Yeh, YJ Luo, R Olsen, SA Lim, J Hu, P Jin, J Song 28/10/2020 Neurobiology of disease
Y Lin, J Xue, J Deng, H He, S Luo, J Chen, J Li, L Yu, J Zhao, J Chen, EG Allen, P Jin, R Duan 01/09/2020 Publisher Correction: Integrated analysis of a compendium of RNA-Seq datasets for splicing factors.
Scientific data
P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin 07/08/2020 Integrated analysis of a compendium of RNA-Seq datasets for splicing factors.
Scientific data
P Yu, J Li, SP Deng, F Zhang, PN Grozdanov, EWM Chin, SD Martin, L Vergnes, MS Islam, D Sun, JM LaSalle, SL McGee, E Goh, CC MacDonald, P Jin 16/06/2020 Robust partial reference-free cell composition estimation from tissue expression.
Bioinformatics (Oxford, England)
Z Li, Z Guo, Y Cheng, P Jin, H Wu 01/06/2020 Molecular genetics & genomic medicine
F Gao, W Huang, Y You, J Huang, J Zhao, J Xue, H Kang, Y Zhu, Z Hu, EG Allen, P Jin, K Xia, R Duan 01/06/2020 Epigenetics
ND Johnson, L Huang, R Li, Y Li, Y Yang, HR Kim, C Grant, H Wu, EA Whitsel, DP Kiel, AA Baccarelli, P Jin, JM Murabito, KN Conneely 01/03/2020 Regulatory annotation of genomic intervals based on tissue-specific expression QTLs.
Bioinformatics (Oxford, England)
T Xu, P Jin, ZS Qin 01/02/2020 Dynamic N6-methyladenosine RNA methylation in brain and diseases.
Epigenomics
AM Shafik, EG Allen, P Jin 01/02/2020 Journal of ovarian research
L Cheng, K Zhang, Y Qing, D Li, M Cui, P Jin, T Xu 22/01/2020 A comprehensive review of computational prediction of genome-wide features.
Briefings in bioinformatics
T Xu, X Zheng, B Li, P Jin, Z Qin, H Wu 17/01/2020 Grainyhead-like 2 as a double-edged sword in development and cancer.
American journal of translational research
J He, C Feng, H Zhu, S Wu, P Jin, T Xu 01/01/2020 Metabolic Alterations in FMR1 Premutation Carriers.
Frontiers in molecular biosciences
Y Cao, Y Peng, HE Kong, EG Allen, P Jin 01/01/2020 Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer's disease.
Human molecular genetics
L Qin, Q Xu, Z Li, L Chen, Y Li, N Yang, Z Liu, J Guo, L Shen, EG Allen, C Chen, C Ma, H Wu, X Zhu, P Jin, B Tang 01/01/2020 Altered 5-Hydroxymethylcytosine Landscape in Primary Gastric Adenocarcinoma.
DNA and cell biology
H Liu, T Xu, Y Cheng, MH Jin, MY Chang, Q Shu, EG Allen, P Jin, X Wang 01/12/2019 Diverse and dynamic DNA modifications in brain and diseases.
Human molecular genetics
MJ Armstrong, Y Jin, EG Allen, P Jin 21/11/2019 Dissecting differential signals in high-throughput data from complex tissues.
Bioinformatics (Oxford, England)
Z Li, Z Wu, P Jin, H Wu 15/10/2019 Neurobiology of disease
H He, W Huang, R Wang, Y Lin, Y Guo, J Deng, H Deng, Y Zhu, EG Allen, P Jin, R Duan 01/10/2019 Current biology : CB
PK Byun, C Zhang, B Yao, J Wardwell-Ozgo, D Terry, P Jin, K Moberg 09/09/2019 Biological psychiatry
Y Cheng, P Jin 15/08/2019 Rare variants in MYH15 modify amyotrophic lateral sclerosis risk.
Human molecular genetics
H Kim, J Lim, H Bao, B Jiao, SM Canon, MP Epstein, K Xu, J Jiang, J Parameswaran, Y Li, KH Moberg, JE Landers, C Fournier, EG Allen, JD Glass, TS Wingo, P Jin 15/07/2019 Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders.
American journal of human genetics
Y Tian, JL Wang, W Huang, S Zeng, B Jiao, Z Liu, Z Chen, Y Li, Y Wang, HX Min, XJ Wang, Y You, RX Zhang, XY Chen, F Yi, YF Zhou, HY Long, CJ Zhou, X Hou, JP Wang, B Xie, F Liang, ZY Yang, QY Sun, EG Allen, AM Shafik, HE Kong, JF Guo, XX Yan, ZM Hu, K Xia, H Jiang, HW Xu, RH Duan, P Jin, BS Tang, L Shen 03/07/2019 Disease prediction by cell-free DNA methylation.
Briefings in bioinformatics
H Feng, P Jin, H Wu 25/03/2019 Human molecular genetics
HE Kong, J Lim, F Zhang, L Huang, Y Gu, DL Nelson, EG Allen, P Jin 15/03/2019 Reversing Behavioral, Neuroanatomical, and Germline Influences of Intergenerational Stress.
Biological psychiatry
HS Aoued, S Sannigrahi, N Doshi, FG Morrison, H Linsenbaum, SC Hunter, H Walum, J Baman, B Yao, P Jin, KJ Ressler, BG Dias 01/02/2019 Application of Drosophila Model Toward Understanding the Molecular Basis of Fragile X Syndrome.
Methods in molecular biology (Clifton, N.J.)
HE Kong, J Lim, P Jin 01/01/2019 Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.
Cell reports
Y Cheng, M Sun, L Chen, Y Li, L Lin, B Yao, Z Li, Z Wang, J Chen, Z Miao, N Xin, L Huang, EG Allen, H Wu, X Xu, P Jin 11/12/2018 Nature neuroscience
Y Cheng, ZM Wang, W Tan, X Wang, Y Li, B Bai, Y Li, SF Zhang, HL Yan, ZL Chen, CM Liu, TW Mi, S Xia, Z Zhou, A Liu, GB Tang, C Liu, ZJ Dai, YY Wang, H Wang, X Wang, Y Kang, L Lin, Z Chen, N Xie, Q Sun, W Xie, J Peng, D Chen, ZQ Teng, P Jin 01/12/2018 Human molecular genetics
F Zhang, Y Kang, M Wang, Y Li, T Xu, W Yang, H Song, H Wu, Q Shu, P Jin 15/11/2018 Molecular cell
B Yao, Y Li, Z Wang, L Chen, M Poidevin, C Zhang, L Lin, F Wang, H Bao, B Jiao, J Lim, Y Cheng, L Huang, BL Phillips, T Xu, R Duan, KH Moberg, H Wu, P Jin 06/09/2018 5-Hydroxymethylcytosine alterations in the human postmortem brains of autism spectrum disorder.
Human molecular genetics
Y Cheng, Z Li, S Manupipatpong, L Lin, X Li, T Xu, YH Jiang, Q Shu, H Wu, P Jin 01/09/2018 GigaScience
X Sun, J Gao, P Jin, C Eng, EG Burchard, TH Beaty, I Ruczinski, RA Mathias, K Barnes, F Wang, ZS Qin 01/06/2018 Genome biology
B Yao, P Jin 10/04/2018 Developing DNA methylation-based diagnostic biomarkers.
Journal of genetics and genomics = Yi chuan xue bao
H Kim, X Wang, P Jin 20/02/2018 Medical genetics: Towards precision medicine.
Journal of genetics and genomics = Yi chuan xue bao
P Jin 20/02/2018 Piperine ameliorates SCA17 neuropathology by reducing ER stress.
Molecular neurodegeneration
J Guo, Y Cui, Q Liu, Y Yang, Y Li, L Weng, B Tang, P Jin, XJ Li, S Yang, S Li 30/01/2018 Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Neuron
YL Weng, X Wang, R An, J Cassin, C Vissers, Y Liu, Y Liu, T Xu, X Wang, SZH Wong, J Joseph, LC Dore, Q Dong, W Zheng, P Jin, H Wu, B Shen, X Zhuang, C He, K Liu, H Song, GL Ming 17/01/2018 Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.
Cell
KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass, D Jimenez-Cyrus, Y Su, NS Kim, Y Zhu, L Zheng, S Kim, X Wang, LC Doré, P Jin, S Regot, X Zhuang, S Canzar, C He, GL Ming, H Song 02/11/2017 DNA N6-methyladenine is dynamically regulated in the mouse brain following environmental stress.
Nature communications
B Yao, Y Cheng, Z Wang, Y Li, L Chen, L Huang, W Zhang, D Chen, H Wu, B Tang, P Jin 24/10/2017 Cell stem cell
KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho, NS Kim, C Habela, L Zheng, F Jacob, F Zhang, EM Lee, WK Huang, FR Ringeling, C Vissers, C Li, L Yuan, K Kang, S Kim, J Yeo, Y Cheng, S Liu, Z Wen, CF Qin, Q Wu, KM Christian, H Tang, P Jin, Z Xu, J Qian, H Zhu, H Song, GL Ming 07/09/2017 Zika virus directly infects peripheral neurons and induces cell death.
Nature neuroscience
Y Oh, F Zhang, Y Wang, EM Lee, IY Choi, H Lim, F Mirakhori, R Li, L Huang, T Xu, H Wu, C Li, CF Qin, Z Wen, QF Wu, H Tang, Z Xu, P Jin, H Song, GL Ming, G Lee 01/09/2017 Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.
Human molecular genetics
L Li, L Zang, F Zhang, J Chen, H Shen, L Shu, F Liang, C Feng, D Chen, H Tao, T Xu, Z Li, Y Kang, H Wu, L Tang, P Zhang, P Jin, Q Shu, X Li 01/07/2017 CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington's disease.
The Journal of clinical investigation
S Yang, R Chang, H Yang, T Zhao, Y Hong, HE Kong, X Sun, Z Qin, P Jin, S Li, XJ Li 30/06/2017 Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis.
Nature communications
X Li, B Yao, L Chen, Y Kang, Y Li, Y Cheng, L Li, L Lin, Z Wang, M Wang, F Pan, Q Dai, W Zhang, H Wu, Q Shu, Z Qin, C He, M Xu, P Jin 29/06/2017 A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association
J Zhao, Y Zhu, J Yang, L Li, H Wu, PL De Jager, P Jin, DA Bennett 01/06/2017 Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Nature communications
F Pan, TS Wingo, Z Zhao, R Gao, H Makishima, G Qu, L Lin, M Yu, JR Ortega, J Wang, A Nazha, L Chen, B Yao, C Liu, S Chen, O Weeks, H Ni, BL Phillips, S Huang, J Wang, C He, GM Li, T Radivoyevitch, I Aifantis, JP Maciejewski, FC Yang, P Jin, M Xu 25/04/2017 Frontiers in cellular neuroscience
HE Kong, J Zhao, S Xu, P Jin, Y Jin 01/01/2017 Genome biology
L Chen, P Jin, ZS Qin 06/12/2016 Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress.
Neurobiology of disease
LA Papale, S Li, A Madrid, Q Zhang, L Chen, P Chopra, P Jin, S Keleş, RS Alisch 01/12/2016 Distinctive Klf4 mutants determine preference for DNA methylation status.
Nucleic acids research
H Hashimoto, D Wang, AN Steves, P Jin, RM Blumenthal, X Zhang, X Cheng 01/12/2016 Structural dynamics control the MicroRNA maturation pathway.
Nucleic acids research
P Dallaire, H Tan, K Szulwach, C Ma, P Jin, F Major 16/11/2016 Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.
Nature neuroscience
A Nott, J Cheng, F Gao, YT Lin, E Gjoneska, T Ko, P Minhas, AV Zamudio, J Meng, F Zhang, P Jin, LH Tsai 01/11/2016 Experimental and molecular pathology
JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki 14/10/2016 Molecular signatures associated with ZIKV exposure in human cortical neural progenitors.
Nucleic acids research
F Zhang, C Hammack, SC Ogden, Y Cheng, EM Lee, Z Wen, X Qian, HN Nguyen, Y Li, B Yao, M Xu, T Xu, L Chen, Z Wang, H Feng, WK Huang, KJ Yoon, C Shan, L Huang, Z Qin, KM Christian, PY Shi, M Xu, M Xia, W Zheng, H Wu, H Song, H Tang, GL Ming, P Jin 14/10/2016 Epigenetic mechanisms in neurogenesis.
Nature reviews. Neuroscience
B Yao, KM Christian, C He, P Jin, GL Ming, H Song 01/09/2016 Human molecular genetics
AI Bernstein, Y Lin, RC Street, L Lin, Q Dai, L Yu, H Bao, M Gearing, JJ Lah, PT Nelson, C He, AI Levey, JG Mullé, R Duan, P Jin 15/06/2016 Human molecular genetics
M Sun, MM Song, B Wei, Q Gao, L Li, B Yao, L Chen, L Lin, Q Dai, X Zhou, J Tao, J Chen, C He, P Jin, Z Xu 01/06/2016 Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.
BMC genomics
L Shu, W Sun, L Li, Z Xu, L Lin, P Xie, H Shen, L Huang, Q Xu, P Jin, X Li 20/05/2016 Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.
Cell
X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack, B Yao, GR Hamersky, F Jacob, C Zhong, KJ Yoon, W Jeang, L Lin, Y Li, J Thakor, DA Berg, C Zhang, E Kang, M Chickering, D Nauen, CY Ho, Z Wen, KM Christian, PY Shi, BJ Maher, H Wu, P Jin, H Tang, H Song, GL Ming 19/05/2016 Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth.
Cell stem cell
H Tang, C Hammack, SC Ogden, Z Wen, X Qian, Y Li, B Yao, J Shin, F Zhang, EM Lee, KM Christian, RA Didier, P Jin, H Song, GL Ming 05/05/2016 DNA methylation dynamics in neurogenesis.
Epigenomics
Z Wang, B Tang, Y He, P Jin 01/03/2016 Neurobiology of disease
S Li, LA Papale, Q Zhang, A Madrid, L Chen, P Chopra, S Keleş, P Jin, RS Alisch 01/02/2016 eLife
J Weber, H Bao, C Hartlmüller, Z Wang, A Windhager, R Janowski, T Madl, P Jin, D Niessing 08/01/2016 Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression.
Molecular cell
Y Zeng, B Yao, J Shin, L Lin, N Kim, Q Song, S Liu, Y Su, JU Guo, L Huang, J Wan, H Wu, J Qian, X Cheng, H Zhu, GL Ming, P Jin, H Song 07/01/2016 Frontiers in genetics
JA Gross, C Nagy, L Lin, É Bonneil, M Maheu, P Thibault, N Mechawar, P Jin, G Turecki 01/01/2016 The Drosophila Helicase MLE Targets Hairpin Structures in Genomic Transcripts.
PLoS genetics
S Cugusi, Y Li, P Jin, JC Lucchesi 01/01/2016 Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons.
Cell stem cell
L Zhang, JC Yin, H Yeh, NX Ma, G Lee, XA Chen, Y Wang, L Lin, L Chen, P Jin, GY Wu, G Chen 03/12/2015 DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Nature communications
AP Wingo, LM Almli, JS Stevens, T Klengel, M Uddin, Y Li, AC Bustamante, A Lori, N Koen, DJ Stein, AK Smith, AE Aiello, KC Koenen, DE Wildman, S Galea, B Bradley, EB Binder, P Jin, G Gibson, KJ Ressler 03/12/2015 Nucleic acids research
H Wu, T Xu, H Feng, L Chen, B Li, B Yao, Z Qin, P Jin, KN Conneely 02/12/2015 Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Cell reports
Z Zhao, L Chen, MM Dawlaty, F Pan, O Weeks, Y Zhou, Z Cao, H Shi, J Wang, L Lin, S Chen, W Yuan, Z Qin, H Ni, SD Nimer, FC Yang, R Jaenisch, P Jin, M Xu 24/11/2015 Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury.
Human molecular genetics
Z Miao, Y He, N Xin, M Sun, L Chen, L Lin, J Li, J Kong, P Jin, X Xu 15/10/2015 The Journal of biological chemistry
J Zeng, R Mi, Y Wang, Y Li, L Lin, B Yao, L Song, I van Die, AB Chapman, RD Cummings, P Jin, T Ju 31/07/2015 Developmental cell
C Zhang, BS Robinson, W Xu, L Yang, B Yao, H Zhao, PK Byun, P Jin, A Veraksa, KH Moberg 27/07/2015 DNA methylation and hydroxymethylation in stem cells.
Cell biochemistry and function
Y Cheng, N Xie, P Jin, T Wang 01/06/2015 5-Hydroxymethylcytosine: A new player in brain disorders?
Experimental neurology
Y Cheng, A Bernstein, D Chen, P Jin 01/06/2015 Molecular and cellular biology
J Hanus, H Zhang, DH Chen, Q Zhou, P Jin, Q Liu, S Wang 01/06/2015 Role of Tet1 and 5-hydroxymethylcytosine in cocaine action.
Nature neuroscience
J Feng, N Shao, KE Szulwach, V Vialou, J Huynh, C Zhong, T Le, D Ferguson, ME Cahill, Y Li, JW Koo, E Ribeiro, B Labonte, BM Laitman, D Estey, V Stockman, P Kennedy, T Couroussé, I Mensah, G Turecki, KF Faull, GL Ming, H Song, G Fan, P Casaccia, L Shen, P Jin, EJ Nestler 01/04/2015 Base-resolution methylation patterns accurately predict transcription factor bindings in vivo.
Nucleic acids research
T Xu, B Li, M Zhao, KE Szulwach, RC Street, L Lin, B Yao, F Zhang, P Jin, H Wu, ZS Qin 11/03/2015 Cancer cell
L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ER Wright, D Duong, NT Seyfried, R Egnatchik, RJ DeBerardinis, KR Magliocca, C He, ML Arellano, HJ Khoury, DM Shin, FR Khuri, S Kang 09/02/2015 Proceedings of the National Academy of Sciences of the United States of America
LK Myrick, PY Deng, H Hashimoto, YM Oh, Y Cho, MJ Poidevin, JA Suhl, J Visootsak, V Cavalli, P Jin, X Cheng, ST Warren, VA Klyachko 27/01/2015 Small-molecule screening using Drosophila models of human neurological disorders.
Methods in molecular biology (Clifton, N.J.)
M Poidevin, F Zhang, P Jin 01/01/2015 Nature communications
H Li, X Zhong, KF Chau, NJ Santistevan, W Guo, G Kong, X Li, M Kadakia, J Masliah, J Chi, P Jin, J Zhang, X Zhao, Q Chang 25/11/2014 Human molecular genetics
JN Galloway, C Shaw, P Yu, D Parghi, M Poidevin, P Jin, DL Nelson 15/11/2014 Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus.
Genomics
H Irier, RC Street, R Dave, L Lin, C Cai, TH Davis, B Yao, Y Cheng, P Jin 01/11/2014 Human molecular genetics
W Zhang, Y Cheng, Y Li, Z Chen, P Jin, D Chen 01/10/2014 Towards understanding RNA-mediated neurological disorders.
Journal of genetics and genomics = Yi chuan xue bao
R Duan, S Sharma, Q Xia, K Garber, P Jin 20/09/2014 AGO3 Slicer activity regulates mitochondria-nuage localization of Armitage and piRNA amplification.
The Journal of cell biology
H Huang, Y Li, KE Szulwach, G Zhang, P Jin, D Chen 21/07/2014 Unlocking epigenetic codes in neurogenesis.
Genes & development
B Yao, P Jin 15/06/2014 Human molecular genetics
L Lin, CM Hales, K Garber, P Jin 15/06/2014 Stem cell reports
G Zhu, Y Li, F Zhu, T Wang, W Jin, W Mu, W Lin, W Tan, W Li, RC Street, S Peng, J Zhang, Y Feng, ST Warren, Q Sun, P Jin, D Chen 11/03/2014 Human molecular genetics
B Yao, L Lin, RC Street, ZA Zalewski, JN Galloway, H Wu, DL Nelson, P Jin 15/02/2014 Cytosine modifications in neurodevelopment and diseases.
Cellular and molecular life sciences : CMLS
B Yao, P Jin 01/02/2014 Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain.
Frontiers in biology
JU Guo, KE Szulwach, Y Su, Y Li, B Yao, Z Xu, JH Shin, B Xie, Y Gao, GL Ming, P Jin, H Song 01/02/2014 Integrating DNA methylation dynamics into a framework for understanding epigenetic codes.
BioEssays : news and reviews in molecular, cellular and developmental biology
KE Szulwach, P Jin 01/01/2014 Journal of neurodevelopmental disorders
SL Sherman, EC Curnow, CA Easley, P Jin, RK Hukema, MI Tejada, R Willemsen, K Usdin 01/01/2014 Toward pluripotency by reprogramming: mechanisms and application.
Protein & cell
T Wang, ST Warren, P Jin 01/11/2013 Probing the microRNA pathway with small molecules.
Bioorganic & medicinal chemistry
Y Li, P Ji, P Jin 15/10/2013 U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
B Bai, CM Hales, PC Chen, Y Gozal, EB Dammer, JJ Fritz, X Wang, Q Xia, DM Duong, C Street, G Cantero, D Cheng, DR Jones, Z Wu, Y Li, I Diner, CJ Heilman, HD Rees, H Wu, L Lin, KE Szulwach, M Gearing, EJ Mufson, DA Bennett, TJ Montine, NT Seyfried, TS Wingo, YE Sun, P Jin, J Hanfelt, DM Willcock, A Levey, JJ Lah, J Peng 08/10/2013 TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Proceedings of the National Academy of Sciences of the United States of America
H Huang, X Jiang, Z Li, Y Li, CX Song, C He, M Sun, P Chen, S Gurbuxani, J Wang, GM Hong, AG Elkahloun, S Arnovitz, J Wang, K Szulwach, L Lin, C Street, M Wunderlich, M Dawlaty, MB Neilly, R Jaenisch, FC Yang, JC Mulloy, P Jin, PP Liu, JD Rowley, M Xu, C He, J Chen 16/07/2013 Nature cell biology
T Wang, H Wu, Y Li, KE Szulwach, L Lin, X Li, IP Chen, IS Goldlust, SJ Chamberlain, A Dodd, H Gong, G Ananiev, JW Han, YS Yoon, MK Rudd, M Yu, CX Song, C He, Q Chang, ST Warren, P Jin 01/06/2013 Proceedings of the National Academy of Sciences of the United States of America
Z Xu, M Poidevin, X Li, Y Li, L Shu, DL Nelson, H Li, CM Hales, M Gearing, TS Wingo, P Jin 07/05/2013 Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
Cell
CX Song, KE Szulwach, Q Dai, Y Fu, SQ Mao, L Lin, C Street, Y Li, M Poidevin, H Wu, J Gao, P Liu, L Li, GL Xu, P Jin, C He 25/04/2013 Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Nature communications
L Zhang, KE Szulwach, GC Hon, CX Song, B Park, M Yu, X Lu, Q Dai, X Wang, CR Street, H Tan, JH Min, B Ren, P Jin, C He 01/01/2013 Nature communications
T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, M Alečković, G LeRoy, Y Kang, HB Kang, JH Seo, C Shan, P Jin, W Gong, S Lonial, ML Arellano, HJ Khoury, GZ Chen, DM Shin, FR Khuri, TJ Boggon, S Kang, C He, J Chen 01/01/2013 Stem cell reports
AM Singh, J Chappell, R Trost, L Lin, T Wang, J Tang, BK Matlock, KP Weller, H Wu, S Zhao, P Jin, S Dalton 01/01/2013 Human molecular genetics
T Wang, Q Pan, L Lin, KE Szulwach, CX Song, C He, H Wu, ST Warren, P Jin, R Duan, X Li 15/12/2012 Epigenetics-Based Therapeutics for Neurodegenerative Disorders.
Current translational geriatrics and experimental gerontology reports
Z Xu, H Li, P Jin 01/12/2012 SRPK2 phosphorylates tau and mediates the cognitive defects in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Y Hong, CB Chan, IS Kwon, X Li, M Song, HP Lee, X Liu, P Sompol, P Jin, HG Lee, SP Yu, K Ye 28/11/2012 Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.
Cancer cell
T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, L Zhang, J Xie, TL Gu, P Jin, M Alečković, G LeRoy, Y Kang, JA Sudderth, RJ DeBerardinis, CH Luan, GZ Chen, S Muller, DM Shin, TK Owonikoko, S Lonial, ML Arellano, HJ Khoury, FR Khuri, BH Lee, K Ye, TJ Boggon, S Kang, C He, J Chen 13/11/2012 Selective capture of 5-hydroxymethylcytosine from genomic DNA.
Journal of visualized experiments : JoVE
Y Li, CX Song, C He, P Jin 05/10/2012 Dynamics of DNA methylation in aging and Alzheimer's disease.
DNA and cell biology
HA Irier, P Jin 01/10/2012 Stable isotope labeling with amino acids in Drosophila for quantifying proteins and modifications.
Journal of proteome research
P Xu, H Tan, DM Duong, Y Yang, J Kupsco, KH Moberg, H Li, P Jin, J Peng 07/09/2012 5-Hydroxymethylcytosine (5-hmC) Specific Enrichment.
Bio-protocol
KE Szulwach, CX Song, C He, P Jin 05/08/2012 RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome.
Brain research
Y Li, P Jin 26/06/2012 Iron homeostasis regulates the activity of the microRNA pathway through poly(C)-binding protein 2.
Cell metabolism
Y Li, L Lin, Z Li, X Ye, K Xiong, B Aryal, Z Xu, Z Paroo, Q Liu, C He, P Jin 06/06/2012 Role of noncoding RNAs in trinucleotide repeat neurodegenerative disorders.
Experimental neurology
H Tan, Z Xu, P Jin 01/06/2012 Human molecular genetics
A Qurashi, H Liu, L Ray, DL Nelson, R Duan, P Jin 01/05/2012 Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration.
Human molecular genetics
H Tan, A Qurashi, M Poidevin, DL Nelson, H Li, P Jin 01/01/2012 MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats.
PLoS genetics
H Tan, M Poidevin, H Li, D Chen, P Jin 01/01/2012 Fragile X mental retardation protein and stem cells.
Results and problems in cell differentiation
A Qurashi, X Li, P Jin 01/01/2012 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Nature neuroscience
KE Szulwach, X Li, Y Li, CX Song, H Wu, Q Dai, H Irier, AK Upadhyay, M Gearing, AI Levey, A Vasanthakumar, LA Godley, Q Chang, X Cheng, C He, P Jin 30/10/2011 RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression.
Neuron
W Guo, L Zhang, DM Christopher, ZQ Teng, SR Fausett, C Liu, OL George, J Klingensmith, P Jin, X Zhao 09/06/2011 Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells.
PLoS genetics
KE Szulwach, X Li, Y Li, CX Song, JW Han, S Kim, S Namburi, K Hermetz, JJ Kim, MK Rudd, YS Yoon, B Ren, C He, P Jin 01/06/2011 PLoS genetics
A Qurashi, W Li, JY Zhou, J Peng, P Jin 01/06/2011 Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Nature biotechnology
CX Song, KE Szulwach, Y Fu, Q Dai, C Yi, X Li, Y Li, CH Chen, W Zhang, X Jian, J Wang, L Zhang, TJ Looney, B Zhang, LA Godley, LM Hicks, BT Lahn, P Jin, C He 01/01/2011 Emergence of chemical biology approaches to the RNAi/miRNA pathway.
Chemistry & biology
Y Li, C He, P Jin 25/06/2010 MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1.
Stem cells (Dayton, Ohio)
RD Smrt, KE Szulwach, RL Pfeiffer, X Li, W Guo, M Pathania, ZQ Teng, Y Luo, J Peng, A Bordey, P Jin, X Zhao 01/06/2010 Roles of small regulatory RNAs in determining neuronal identity.
Nature reviews. Neuroscience
X Li, P Jin 01/05/2010 Cross talk between microRNA and epigenetic regulation in adult neurogenesis.
The Journal of cell biology
KE Szulwach, X Li, RD Smrt, Y Li, Y Luo, L Lin, NJ Santistevan, W Li, X Zhao, P Jin 05/04/2010 Small RNA-mediated gene regulation in neurodevelopmental disorders.
Current psychiatry reports
A Qurashi, P Jin 01/04/2010 RNA-mediated pathogenesis in fragile X-associated disorders.
Neuroscience letters
H Tan, H Li, P Jin 04/12/2009 Germline mutation of microRNA-125a is associated with breast cancer.
Journal of medical genetics
W Li, R Duan, F Kooy, SL Sherman, W Zhou, P Jin 01/05/2009 Small regulatory RNAs in neurodevelopmental disorders.
Human molecular genetics
S Chang, S Wen, D Chen, P Jin 15/04/2009 Noncoding RNAs in mental retardation.
Clinical genetics
KE Szulwach, P Jin, RS Alisch 01/03/2009 Macro role(s) of microRNAs in fragile X syndrome?
Neuromolecular medicine
X Li, P Jin 01/01/2009 The microRNA pathway and fragile X mental retardation protein.
Biochimica et biophysica acta
Y Li, L Lin, P Jin 01/11/2008 A small molecule enhances RNA interference and promotes microRNA processing.
Nature biotechnology
G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, L Lu, Z Paroo, AW Chan, Z Shi, Q Liu, C Wahlestedt, C He, P Jin 01/08/2008 Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila.
Nature chemical biology
S Chang, SM Bray, Z Li, DC Zarnescu, C He, P Jin, ST Warren 01/04/2008 FXTAS: a bad RNA and a hope for a cure.
Expert opinion on biological therapy
G Shan, S Xu, P Jin 01/03/2008