John Altman, PhD
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Research Program
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Phone Number
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Email Address
John D. Altman, PhD, is an associate professor in the Department of Microbiology and Immunology at Emory University School of Medicine. Dr. Altman is a member of the Cancer Immunology Research Program at Winship Cancer Institute of Emory University.
Dr. Altman earned his PhD in pharmaceutical chemistry from the University of California, San Francisco, and completed his postdoctoral training at Stanford University.
Dr. Altman pioneered the development of tetramer reagents, which can be customized for individual studies to provide extremely precise measures of immune response. He heads the Tetramer Core, funded by the National Institute of Allergy and Infectious Diseases as a service for NIH-approved investigators throughout the U.S. He also directs the Emory CFAR Immunology Core, which provides immunology assay service for investigators through Emory's Center for AIDS Research.
Grant Number | Title |
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75N93020D00005-0-759302000001-1 | NIH TETRAMER CORE FACILITY (HIV/AIDS) |
75N93020D00005-0-759302000001-2 | NIH TETRAMER CORE FACILITY (INFECTIOUS DISEASES OTHER THAN HIV/AIDS) |
75N93020D00005-0-759302000003-1 | NIH TCF Dev and Prod of SARS-CoV-2 Spike tetramers for B Cell Detection |
75N93020D00005-P00002-759302000001-1 | NIH TETRAMER CORE FACILITY (HIV/AIDS) |
75N93020D00005-P00002-759302000001-2 | NIH TETRAMER CORE FACILITY (INFECTIOUS DISEASES OTHER THAN HIV/AIDS) |
75N93020D00005-P00003-759302000001-1 | NIH TETRAMER CORE FACILITY (HIV/AIDS) |
75N93020D00005-P00003-759302000001-2 | NIH TETRAMER CORE FACILITY (INFECTIOUS DISEASES OTHER THAN HIV/AIDS) |
75N93020D00005-P00004-759302000001-1 | NIH TETRAMER CORE FACILITY (HIV/AIDS) |
75N93020D00005-P00004-759302000001-2 | TASK A-1: NIH TETRAMER CORE FACILITY (INFECTIOUS DISEASES OTHER THAN HIV/AIDS) |
75N93020D00005-P00005-759302000001-1 | NIH TETRAMER CORE FACILITY (HIV/AIDS) |
Title/Journal | Authors | Publication Date |
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Cell reports |
MK Tenggara, SH Oh, C Yang, HK Nariya, AM Metz, AA Upadhyay, DR Gudipati, L Guo, EG McGhee, K Gill, EG Viox, RD Mason, NA Doria-Rose, KE Foulds, JR Mascola, Y Du, H Fu, JD Altman, Q Yan, Z Sheng, SE Bosinger, R Kong | 26/03/2024 |
Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection. bioRxiv : the preprint server for biology |
P Ogongo, L Wassie, A Tran, D Columbus, L Sharling, G Ouma, SG Ouma, K Bobosha, CS Lindestam Arlehamn, NR Gandhi, SC Auld, J Rengarajan, CL Day, JD Altman, HM Blumberg, JD Ernst | 06/03/2024 |
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms. Cell |
S Huang, A Shahine, TY Cheng, YL Chen, SW Ng, GR Balaji, R Farquhar, S Gras, CS Hardman, JD Altman, N Tahiri, AJ Minnaard, GS Ogg, JA Mayfield, J Rossjohn, DB Moody | 12/10/2023 |
The Long-Awaited Respiratory Syncytial Virus Vaccine. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research |
JD Altman, BT Rouse | 01/07/2023 |
Immunity |
F Gao, V Mallajosyula, PS Arunachalam, K van der Ploeg, M Manohar, K Röltgen, F Yang, O Wirz, R Hoh, E Haraguchi, JY Lee, R Willis, V Ramachandiran, J Li, KR Kathuria, C Li, AS Lee, MM Shah, SB Sindher, J Gonzalez, JD Altman, TT Wang, SD Boyd, B Pulendran, P Jagannathan, KC Nadeau, MM Davis | 11/04/2023 |
T cells in COVID-19 - the kids are all right. Nature immunology |
JD Altman | 01/05/2022 |
Minimal Information about MHC Multimers (MIAMM). Journal of immunology (Baltimore, Md. : 1950) |
R Vita, A Mody, JA Overton, S Buus, ST Haley, A Sette, V Mallajosyula, MM Davis, DL Long, RA Willis, B Peters, JD Altman | 01/02/2022 |
CD1a selectively captures endogenous cellular lipids that broadly block T cell response. The Journal of experimental medicine |
RN Cotton, M Wegrecki, TY Cheng, YL Chen, N Veerapen, J Le Nours, DP Orgill, B Pomahac, SG Talbot, R Willis, JD Altman, A de Jong, I Van Rhijn, RA Clark, GS Besra, G Ogg, J Rossjohn, DB Moody | 05/07/2021 |
Journal of immunology (Baltimore, Md. : 1950) |
ED Layton, S Barman, DB Wilburn, KKQ Yu, MT Smith, JD Altman, TJ Scriba, N Tahiri, AJ Minnaard, M Roederer, RA Seder, PA Darrah, C Seshadri | 15/03/2021 |
Current protocols |
RA Willis, V Ramachandiran, JC Shires, G Bai, K Jeter, DL Bell, L Han, T Kazarian, KC Ugwu, O Laur, S Contreras-Alcantara, DL Long, JD Altman | 01/02/2021 |
Journal of acquired immune deficiency syndromes (1999) |
TA McLaughlin, A Nizam, FO Hayara, GS Ouma, A Campbell, J Khayumbi, J Ongalo, SG Ouma, NS Shah, JD Altman, D Kaushal, J Rengarajan, JD Ernst, HM Blumberg, LA Waller, NR Gandhi, CL Day, D Benkeser | 01/02/2021 |
Human skin is colonized by T cells that recognize CD1a independently of lipid. The Journal of clinical investigation |
RN Cotton, TY Cheng, M Wegrecki, J Le Nours, DP Orgill, B Pomahac, SG Talbot, RA Willis, JD Altman, A de Jong, G Ogg, I Van Rhijn, J Rossjohn, RA Clark, DB Moody | 04/01/2021 |
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques. American journal of respiratory and critical care medicine |
TW Foreman, AN Bucşan, S Mehra, C Peloquin, LA Doyle, K Russell-Lodrigue, NR Gandhi, J Altman, CL Day, JD Ernst, HM Blumberg, J Rengarajan, D Kaushal | 15/02/2020 |
Analytical biochemistry |
MM Jurewicz, RA Willis, V Ramachandiran, JD Altman, LJ Stern | 01/11/2019 |
Journal of virology |
MA Martins, L Gonzalez-Nieto, YC Shin, A Domingues, MJ Gutman, HS Maxwell, DM Magnani, MJ Ricciardi, N Pedreño-Lopez, VK Bailey, JD Altman, CL Parks, DB Allison, K Ejima, EG Rakasz, S Capuano, RC Desrosiers, JD Lifson, DI Watkins | 01/03/2019 |
Clinical Events After Deferral of LAD Revascularization Following Physiological Coronary Assessment. Journal of the American College of Cardiology |
S Sen, Y Ahmad, HM Dehbi, JP Howard, JF Iglesias, R Al-Lamee, R Petraco, S Nijjer, R Bhindi, S Lehman, D Walters, J Sapontis, L Janssens, CJ Vrints, A Khashaba, M Laine, E Van Belle, F Krackhardt, W Bojara, O Going, T Härle, C Indolfi, G Niccoli, F Ribichini, N Tanaka, H Yokoi, H Takashima, Y Kikuta, A Erglis, H Vinhas, PC Silva, SB Baptista, A Alghamdi, F Hellig, BK Koo, CW Nam, ES Shin, JH Doh, S Brugaletta, E Alegria-Barrero, M Meuwissen, JJ Piek, N van Royen, M Sezer, C Di Mario, RT Gerber, IS Malik, ASP Sharp, S Talwar, K Tang, H Samady, J Altman, AH Seto, J Singh, A Jeremias, H Matsuo, RK Kharbanda, MR Patel, P Serruys, J Escaned, JE Davies | 05/02/2019 |
Casting a wider net: Immunosurveillance by nonclassical MHC molecules. PLoS pathogens |
MP D'Souza, E Adams, JD Altman, ME Birnbaum, C Boggiano, G Casorati, YH Chien, A Conley, SBG Eckle, K Früh, T Gondré-Lewis, N Hassan, H Huang, L Jayashankar, AG Kasmar, N Kunwar, J Lavelle, DM Lewinsohn, B Moody, L Picker, L Ramachandra, N Shastri, P Parham, AJ McMichael, JW Yewdell | 01/02/2019 |
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nature communications |
A Shahine, P Reinink, JF Reijneveld, S Gras, M Holzheimer, TY Cheng, AJ Minnaard, JD Altman, S Lenz, J Prandi, J Kubler-Kielb, DB Moody, J Rossjohn, I Van Rhijn | 04/01/2019 |
Journal of virology |
MA Martins, DC Tully, N Pedreño-Lopez, B von Bredow, MG Pauthner, YC Shin, M Yuan, NS Lima, DJ Bean, L Gonzalez-Nieto, A Domingues, MJ Gutman, HS Maxwell, DM Magnani, MJ Ricciardi, VK Bailey, JD Altman, DR Burton, K Ejima, DB Allison, DT Evans, EG Rakasz, CL Parks, MC Bonaldo, S Capuano, JD Lifson, RC Desrosiers, TM Allen, DI Watkins | 15/08/2018 |
Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function. eLife |
J Geng, JD Altman, S Krishnakumar, M Raghavan | 09/05/2018 |
Journal of immunology (Baltimore, Md. : 1950) |
WE Whatney, NR Gandhi, CS Lindestam Arlehamn, A Nizam, H Wu, MJ Quezada, A Campbell, S Allana, MM Kabongo, J Khayumbi, B Muchiri, J Ongalo, J Tonui, LE Sasser, TJ Fergus, GS Ouma, SG Ouma, AA Beck, MJ Mulligan, A Oladele, D Kaushal, KP Cain, L Waller, HM Blumberg, JD Altman, JD Ernst, J Rengarajan, CL Day | 15/04/2018 |
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nature immunology |
KS Wun, JF Reijneveld, TY Cheng, K Ladell, AP Uldrich, J Le Nours, KL Miners, JE McLaren, EJ Grant, OL Haigh, TS Watkins, S Suliman, S Iwany, J Jimenez, R Calderon, KL Tamara, SR Leon, MB Murray, JA Mayfield, JD Altman, AW Purcell, JJ Miles, DI Godfrey, S Gras, DA Price, I Van Rhijn, DB Moody, J Rossjohn | 01/04/2018 |
PloS one |
K Li, CK Vorkas, A Chaudhry, DL Bell, RA Willis, A Rudensky, JD Altman, MS Glickman, J Aubé | 01/01/2018 |
PLoS neglected tropical diseases |
MJ Ricciardi, DM Magnani, A Grifoni, YC Kwon, MJ Gutman, ND Grubaugh, K Gangavarapu, M Sharkey, CGT Silveira, VK Bailey, N Pedreño-Lopez, L Gonzalez-Nieto, HS Maxwell, A Domingues, MA Martins, J Pham, D Weiskopf, J Altman, EG Kallas, KG Andersen, M Stevenson, P Lichtenberger, H Choe, SS Whitehead, A Sette, DI Watkins | 01/12/2017 |
Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque. AIDS research and human retroviruses |
MA Martins, DC Tully, YC Shin, L Gonzalez-Nieto, KL Weisgrau, DJ Bean, R Gadgil, MJ Gutman, A Domingues, HS Maxwell, DM Magnani, M Ricciardi, N Pedreño-Lopez, V Bailey, MA Cruz, NS Lima, MC Bonaldo, JD Altman, E Rakasz, S Capuano, KA Reimann, M Piatak, JD Lifson, RC Desrosiers, TM Allen, DI Watkins | 01/08/2017 |
PLoS pathogens |
MA Martins, YC Shin, L Gonzalez-Nieto, A Domingues, MJ Gutman, HS Maxwell, I Castro, DM Magnani, M Ricciardi, N Pedreño-Lopez, V Bailey, D Betancourt, JD Altman, M Pauthner, DR Burton, B von Bredow, DT Evans, M Yuan, CL Parks, K Ejima, DB Allison, E Rakasz, GN Barber, S Capuano, JD Lifson, RC Desrosiers, DI Watkins | 01/07/2017 |
MHC-Peptide Tetramers to Visualize Antigen-Specific T Cells. Current protocols in immunology |
JD Altman, MM Davis | 01/11/2016 |
Molecular Analysis of Lipid-Reactive Vδ1 γδ T Cells Identified by CD1c Tetramers. Journal of immunology (Baltimore, Md. : 1950) |
S Roy, D Ly, CD Castro, NS Li, AJ Hawk, JD Altman, SC Meredith, JA Piccirilli, DB Moody, EJ Adams | 15/02/2016 |
Human autoreactive T cells recognize CD1b and phospholipids. Proceedings of the National Academy of Sciences of the United States of America |
I Van Rhijn, T van Berlo, T Hilmenyuk, TY Cheng, BJ Wolf, RV Tatituri, AP Uldrich, G Napolitani, V Cerundolo, JD Altman, P Willemsen, S Huang, J Rossjohn, GS Besra, MB Brenner, DI Godfrey, DB Moody | 12/01/2016 |
Journal of virology |
MA Martins, DC Tully, MA Cruz, KA Power, MG Veloso de Santana, DJ Bean, CB Ogilvie, R Gadgil, NS Lima, DM Magnani, K Ejima, DB Allison, M Piatak, JD Altman, CL Parks, EG Rakasz, S Capuano, R Galler, MC Bonaldo, JD Lifson, TM Allen, DI Watkins | 01/11/2015 |
JACC. Cardiovascular interventions |
J Escaned, M Echavarría-Pinto, HM Garcia-Garcia, TP van de Hoef, T de Vries, P Kaul, G Raveendran, JD Altman, HI Kurz, J Brechtken, M Tulli, C Von Birgelen, JE Schneider, AA Khashaba, A Jeremias, J Baucum, R Moreno, M Meuwissen, G Mishkel, RJ van Geuns, H Levite, R Lopez-Palop, M Mayhew, PW Serruys, H Samady, JJ Piek, A Lerman | 01/05/2015 |
Proceedings of the National Academy of Sciences of the United States of America |
S Roy, D Ly, NS Li, JD Altman, JA Piccirilli, DB Moody, EJ Adams | 28/10/2014 |
CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nature immunology |
A de Jong, TY Cheng, S Huang, S Gras, RW Birkinshaw, AG Kasmar, I Van Rhijn, V Peña-Cruz, DT Ruan, JD Altman, J Rossjohn, DB Moody | 01/02/2014 |
Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. Journal of immunology (Baltimore, Md. : 1950) |
AG Kasmar, I Van Rhijn, KG Magalhaes, DC Young, TY Cheng, MT Turner, A Schiefner, RC Kalathur, IA Wilson, M Bhati, S Gras, RW Birkinshaw, LL Tan, J Rossjohn, J Shires, S Jakobsen, JD Altman, DB Moody | 01/11/2013 |
A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nature immunology |
I Van Rhijn, A Kasmar, A de Jong, S Gras, M Bhati, ME Doorenspleet, N de Vries, DI Godfrey, JD Altman, W de Jager, J Rossjohn, DB Moody | 01/07/2013 |
CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens. The Journal of experimental medicine |
D Ly, AG Kasmar, TY Cheng, A de Jong, S Huang, S Roy, A Bhatt, RP van Summeren, JD Altman, WR Jacobs, EJ Adams, AJ Minnaard, SA Porcelli, DB Moody | 08/04/2013 |
Platelets support a protective immune response to LCMV by preventing splenic necrosis. Blood |
GD Loria, PA Romagnoli, NB Moseley, A Rucavado, JD Altman | 07/02/2013 |
PloS one |
PA Romagnoli, MF Premenko-Lanier, GD Loria, JD Altman | 01/01/2013 |
Journal of virology |
DA Garber, LA O'Mara, S Gangadhara, M McQuoid, X Zhang, R Zheng, K Gill, M Verma, T Yu, B Johnson, B Li, CA Derdeyn, C Ibegbu, JD Altman, E Hunter, MB Feinberg | 01/12/2012 |
Journal of immunological methods |
NB Moseley, O Laur, CC Ibegbu, GD Loria, G Ikwuenzunma, HR Jayakar, MA Whitt, JD Altman | 31/01/2012 |
Proceedings of the National Academy of Sciences of the United States of America |
S Huang, TY Cheng, DC Young, E Layre, CA Madigan, J Shires, V Cerundolo, JD Altman, DB Moody | 29/11/2011 |
The Journal of experimental medicine |
AG Kasmar, I van Rhijn, TY Cheng, M Turner, C Seshadri, A Schiefner, RC Kalathur, JW Annand, A de Jong, J Shires, L Leon, M Brenner, IA Wilson, JD Altman, DB Moody | 29/08/2011 |
Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis. Nature reviews. Immunology |
MM Davis, JD Altman, EW Newell | 15/07/2011 |
Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96. Journal of immunology (Baltimore, Md. : 1950) |
JD Altman, PA Moss, PJ Goulder, DH Barouch, MG McHeyzer-Williams, JI Bell, AJ McMichael, MM Davis | 01/07/2011 |
The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response. Journal of immunology (Baltimore, Md. : 1950) |
RS Akondy, ND Monson, JD Miller, S Edupuganti, D Teuwen, H Wu, F Quyyumi, S Garg, JD Altman, C Del Rio, HL Keyserling, A Ploss, CM Rice, WA Orenstein, MJ Mulligan, R Ahmed | 15/12/2009 |
The Journal of infectious diseases |
B Pulendran, J Miller, TD Querec, R Akondy, N Moseley, O Laur, J Glidewell, N Monson, T Zhu, H Zhu, S Staprans, D Lee, MA Brinton, AA Perelygin, C Vellozzi, P Brachman, S Lalor, D Teuwen, RB Eidex, M Cetron, F Priddy, C del Rio, J Altman, R Ahmed | 15/08/2008 |
Transient FTY720 treatment promotes immune-mediated clearance of a chronic viral infection. Nature |
M Premenko-Lanier, NB Moseley, ST Pruett, PA Romagnoli, JD Altman | 14/08/2008 |
Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity |
JD Miller, RG van der Most, RS Akondy, JT Glidewell, S Albott, D Masopust, K Murali-Krishna, PL Mahar, S Edupuganti, S Lalor, S Germon, C Del Rio, MJ Mulligan, SI Staprans, JD Altman, MB Feinberg, R Ahmed | 01/05/2008 |
Journal of immunology (Baltimore, Md. : 1950) |
JJ Sabatino, J Shires, JD Altman, ML Ford, BD Evavold | 01/04/2008 |